Cost Effective Treatment for Dually Diagnosed Homeless

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00368524
Recruitment Status : Completed
First Posted : August 24, 2006
Last Update Posted : August 24, 2006
Information provided by:
University of Alabama at Birmingham

Brief Summary:
This randomized controlled trial examined whether an abbreviated treatment using abstinence contingency management for housing and work/training (CM, n=103) with cocaine dependent, non-psychotic, dually diagnosed homeless persons, would show non-inferior outcomes compared to the full treatment (CM+, n=103). It was hypothesized that CM+ would show superior abstinence and retention outcomes, but that CM, with components derived from previously effective behavioral day treatment, would obtain non-inferior outcomes, defined as 75% or more of those observed for the full treatment (CM+) during active treatment months 1-6. The CM+ included all CM components but added behavioral day treatment that included voucher reinforcement of $7.50-15.00, for objective weekly therapeutic goal attainment in five domains of functioning: drug dependence, homelessness, unemployment, non-drug related recreational activities, and behavioral, health, or mental health problems. Abstinence was assessed by observed urine specimen collection and weekly testing weeks 1-52, and randomly, bi-monthly for months 13-18. Abstinence, homelessness, employment and other outcomes were also assessed at baseline, 2, 6, 12, and 18 months.

Condition or disease Intervention/treatment Phase
Cocaine Dependence Mental Disorder Homelessness Unemployment Behavioral: contingency management and behavioral day treatment Not Applicable

Study Type : Interventional  (Clinical Trial)
Enrollment : 160 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Cost Effective Treatment for Dually Diagnosed Homeless
Study Start Date : November 2001
Study Completion Date : November 2005

Primary Outcome Measures :
  1. abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18

Secondary Outcome Measures :
  1. abstinence, housing, employment and other outcomes at 0, 2, 6, 12 and 18 months.

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Accepts Healthy Volunteers:   No

Inclusion Criteria: McKinney Act criteria for homelessness; DSM IV diagnosis for Cocaine Dependence; self-reported use within the last 2 weeks; psychological distress indicated by score of 70 on 1 or more Brief Symptom Inventory scales; willingness to participate; no plans to move from Birmingham area for 18 months;

Exclusion Criteria: cognitive impariment precluding informed consent; requiring immediate inpatient medical treatment

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00368524

Sponsors and Collaborators
University of Alabama at Birmingham
Principal Investigator: Jesse B. Milby, Ph.D. ABPP University of Alabama at Birmingham

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00368524     History of Changes
Other Study ID Numbers: F920822004
1R01DA011789 ( U.S. NIH Grant/Contract )
First Posted: August 24, 2006    Key Record Dates
Last Update Posted: August 24, 2006
Last Verified: August 2006

Keywords provided by University of Alabama at Birmingham:
cocaine dependence
mental disorder
dual diagnoses

Additional relevant MeSH terms:
Cocaine-Related Disorders
Mental Disorders
Psychotic Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Schizophrenia Spectrum and Other Psychotic Disorders