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Cost Effective Treatment for Dually Diagnosed Homeless

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00368524
First Posted: August 24, 2006
Last Update Posted: August 24, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Alabama at Birmingham
  Purpose
This randomized controlled trial examined whether an abbreviated treatment using abstinence contingency management for housing and work/training (CM, n=103) with cocaine dependent, non-psychotic, dually diagnosed homeless persons, would show non-inferior outcomes compared to the full treatment (CM+, n=103). It was hypothesized that CM+ would show superior abstinence and retention outcomes, but that CM, with components derived from previously effective behavioral day treatment, would obtain non-inferior outcomes, defined as 75% or more of those observed for the full treatment (CM+) during active treatment months 1-6. The CM+ included all CM components but added behavioral day treatment that included voucher reinforcement of $7.50-15.00, for objective weekly therapeutic goal attainment in five domains of functioning: drug dependence, homelessness, unemployment, non-drug related recreational activities, and behavioral, health, or mental health problems. Abstinence was assessed by observed urine specimen collection and weekly testing weeks 1-52, and randomly, bi-monthly for months 13-18. Abstinence, homelessness, employment and other outcomes were also assessed at baseline, 2, 6, 12, and 18 months.

Condition Intervention
Cocaine Dependence Mental Disorder Homelessness Unemployment Behavioral: contingency management and behavioral day treatment

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Cost Effective Treatment for Dually Diagnosed Homeless

Further study details as provided by University of Alabama at Birmingham:

Primary Outcome Measures:
  • abused drug abstinence measured by observed urine specimen testing weeks 1-52, and bimonthly months 13-18

Secondary Outcome Measures:
  • abstinence, housing, employment and other outcomes at 0, 2, 6, 12 and 18 months.

Estimated Enrollment: 160
Study Start Date: November 2001
Estimated Study Completion Date: November 2005
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria: McKinney Act criteria for homelessness; DSM IV diagnosis for Cocaine Dependence; self-reported use within the last 2 weeks; psychological distress indicated by score of 70 on 1 or more Brief Symptom Inventory scales; willingness to participate; no plans to move from Birmingham area for 18 months;

Exclusion Criteria: cognitive impariment precluding informed consent; requiring immediate inpatient medical treatment

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00368524


Sponsors and Collaborators
University of Alabama at Birmingham
Investigators
Principal Investigator: Jesse B. Milby, Ph.D. ABPP University of Alabama at Birmingham
  More Information

Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00368524     History of Changes
Other Study ID Numbers: F920822004
1R01DA011789 ( U.S. NIH Grant/Contract )
First Submitted: August 23, 2006
First Posted: August 24, 2006
Last Update Posted: August 24, 2006
Last Verified: August 2006

Keywords provided by University of Alabama at Birmingham:
cocaine dependence
mental disorder
dual diagnoses
homelessness

Additional relevant MeSH terms:
Cocaine-Related Disorders
Mental Disorders
Psychotic Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Schizophrenia Spectrum and Other Psychotic Disorders