Use of Erythromycin in Mustard-Induced Bronchiolitis
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Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Documented chemical exposure
Clinical, spirometric and radiological findings were compatible with BO on High Resolution Computed Tomography (HRCT)
Non-responsiveness to high dose bronchodilator therapy
Radiographic evidence of pneumonia, active tuberculosis, lung carcinoma, or an infection that necessitated the use of an antibiotic
History of cigarette smoking and occupational exposure to toxic agents of hypersensitivity to macrolides
History of treatment with a systemic antibiotic within 7 days before the start of the study
Any investigational medicine within 4 weeks of the study
History of antibiotic injection within 6 weeks before the study
Concomitant Theophylline or Carbamazepine, unless their serum concentrations were regularly monitored
Patients who were in the exacerbation phase of their respiratory complications
Need to use medications interact with macrolides such as Digoxin, Theophylline and Carbamazepine