Cytomegalovirus Reactivation in Cancer Patients Receiving Chemotherapy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00366717
Recruitment Status : Completed
First Posted : August 21, 2006
Last Update Posted : August 21, 2006
Information provided by:
Mackay Memorial Hospital

Brief Summary:
Cytomegalovirus (CMV) infects most of the world population. This study is to understand if chemotherapy will increase the chance of reactivating CMV. The results may help us in determining when treatment is needed and perhaps Why is it needed.

Condition or disease
Cancer Cytomegalovirus

Detailed Description:

Despite CMV reactivation has been clearly described in patients underwent transplantation, this phenomenon has not been studied in patients undergoing chemotherapy. Our purpose is to understand if CMV number increases in monocytic leukocytes during chemotherapy and how is the host response to that changes.

Virus load will be studied by quantitative PCR, host response will be studied by measuring patient's anti-CMV IgG, CMV-associated symptoms, serum IFN-r and TNF-a.

Study Type : Observational
Enrollment : 20 participants
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Study Start Date : June 2005
Study Completion Date : January 2006

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • clinical diagnosis of any cancer
  • chemotherapy is needed for more than 6 months
  • age>20 years old

Exclusion Criteria:

  • those who do not agree to participate

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00366717

Mackay Memorial Hospital
Taipei, Taiwan, 10449
Sponsors and Collaborators
Mackay Memorial Hospital
Principal Investigator: Yen-Ta Lu, MD, PhD. Mackay Memorial Hospital

Additional Information: Identifier: NCT00366717     History of Changes
Other Study ID Numbers: MMH-I-S-144
First Posted: August 21, 2006    Key Record Dates
Last Update Posted: August 21, 2006
Last Verified: January 2006

Keywords provided by Mackay Memorial Hospital:
Cancer under chemotherapy