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Bipolar Disorder in Epilepsy

This study has been completed.
Information provided by (Responsible Party):
Northwell Health Identifier:
First received: August 15, 2006
Last updated: May 15, 2012
Last verified: May 2012
The purpose of this study is to find out how often major mood swings occur in patients treated in a specialty epilepsy center.

Bipolar Disorder

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Bipolar Disorder in Epilepsy

Resource links provided by NLM:

Further study details as provided by Northwell Health:

Enrollment: 102
Study Start Date: August 2006
Study Completion Date: December 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Detailed Description:

Bipolar disorder (a condition of major mood swings) or milder forms of ups and downs in mood may occur with a number to neurological conditions. Recently, one study showed that these mood changes occur fairly often in individuals with epilepsy studied in the general community. We speculate that bipolar symptoms occur with even higher frequency in a tertiary epilepsy center than that encountered in the previous community-based study. The goals of this study are to assess:

  • the rate of bipolar symptoms as measured by a self-reporting screening tool in a tertiary epilepsy center setting
  • the meaning of a positive screening score in epilepsy patients
  • the utility, sensitivity and specificity of alternative screening tools for mood instability in epilepsy patients
  • the correlation of mood instability with seizure-related variables
  • the relation of a positive screening score on quality of life.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Epilepsy patients at the Long Island Jewish Comprehensive Epilepsy Center

Inclusion Criteria:

  • Male or female 18 years of age or older
  • Being evaluated at the Long Island Jewish Comprehensive Epilepsy Center
  • Capable of completing self-reporting questionnaires

Exclusion Criteria:

  • Patients with mental retardation
  • Patients with pseudoseizures
  Contacts and Locations
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Please refer to this study by its identifier: NCT00365482

United States, New York
North Shore Long Island Jewish Health System
Great Neck, New York, United States, 11021
Sponsors and Collaborators
Northwell Health
Principal Investigator: Sean Hwang, MD Long Island Jewish Medical Center
  More Information

Responsible Party: Northwell Health Identifier: NCT00365482     History of Changes
Other Study ID Numbers: 06.02.029 
Study First Received: August 15, 2006
Last Updated: May 15, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Northwell Health:
Bipolar Disorder

Additional relevant MeSH terms:
Bipolar Disorder
Pathologic Processes
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Bipolar and Related Disorders
Mental Disorders processed this record on October 27, 2016