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Progression of Hematopoietic Diseases in Shanghai, China

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ClinicalTrials.gov Identifier: NCT00365014
Recruitment Status : Completed
First Posted : August 16, 2006
Last Update Posted : July 23, 2013
Sponsor:
Collaborators:
Fudan University
University of Cincinnati
ExxonMobil Biomedical Sciences, Inc.
British Petroleum P.L.C.
Chevron Corporation
ConocoPhillips
Exxon Mobil
Marathon Ashland
Shell Chemicals
Information provided by (Responsible Party):
University of Colorado, Denver

Brief Summary:
The purpose of this study is to identify and characterize blood diseases presenting at Shanghai hospitals and to compare them with respect to clinical presentation, phenotype, molecular characteristics, benzene or other exposures and genetic susceptibility.

Condition or disease
Hematologic Diseases

Detailed Description:
The purpose of this study is to identify and characterize blood diseases presenting at Shanghai hospitals and to compare them with respect to clinical presentation, phenotype, molecular characteristics, benzene or other exposures and genetic susceptibility. The format for these studies is a set of clinical series superimposed on a case-control design that enables integration of detailed clinical and molecular characterizations of disease pathogenesis together with an evaluation of potential confounding and interacting factors within a structured statistical analysis of benzene exposure.

Study Type : Observational
Actual Enrollment : 10757 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Analysis of Disease Progression for Aplastic Anemia, Myelodysplastic Syndrome, Acute Myeloid Leukemia and Benzene Poisoning in Shanghai, China.
Study Start Date : August 2003
Actual Primary Completion Date : December 2009
Actual Study Completion Date : December 2009


Group/Cohort
Blood disease patients
People with blood diseases presenting at Shanghai hospitals



Primary Outcome Measures :
  1. blood diseases presenting at Shanghai hospitals [ Time Frame: hospital stay ]
    characterization of people with blood diseases presenting at Shanghai hospitals



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with blood diseases
Criteria

Inclusion Criteria:

Men and women 18 years or older Diagnosis of hematologic abnormality

Exclusion Criteria:

Children Non hematologic diseases


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00365014


Locations
China
Joint Sino-US Clinical and Molecular Laboratory (JCML)
Shanghai, China, 200032
Sponsors and Collaborators
University of Colorado, Denver
Fudan University
University of Cincinnati
ExxonMobil Biomedical Sciences, Inc.
British Petroleum P.L.C.
Chevron Corporation
ConocoPhillips
Exxon Mobil
Marathon Ashland
Shell Chemicals
Investigators
Principal Investigator: Richard D Irons, PhD University of Colorado at Denver and Health Sciences Ctr.

Responsible Party: University of Colorado, Denver
ClinicalTrials.gov Identifier: NCT00365014     History of Changes
Other Study ID Numbers: 02-0036
First Posted: August 16, 2006    Key Record Dates
Last Update Posted: July 23, 2013
Last Verified: July 2013

Keywords provided by University of Colorado, Denver:
aplastic anemia
myelodysplastic syndromes
cytopenias
acute myeloid leukemia
myelodysplastic/myeloproliferative diseases
benzene poisoning

Additional relevant MeSH terms:
Myelodysplastic Syndromes
Hematologic Diseases
Bone Marrow Diseases