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Adrenal Function in Patients With Newly Diagnosed Lung Cancer

This study has been completed.
Information provided by:
Princess Margaret Hospital, Hong Kong Identifier:
First received: August 14, 2006
Last updated: January 15, 2009
Last verified: January 2009
Patients with newly diagnosed lung cancer may have hypofunction of the adrenal cortex either from tumour metastasis or other mechanisms. Since lung cancer patient may have to undergo stressful investigation and treatments, undetected hypofunction of the adrenal cortex may be hazardous. Knowledge of the size of the problem may help determine whether routine check is warranted.

Lung Cancer
Adrenal Insufficiency

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Adrenal Cortical Function in Patients With Newly Diagnosed Lung Cancer

Resource links provided by NLM:

Further study details as provided by Princess Margaret Hospital, Hong Kong:

Enrollment: 133
Study Start Date: August 2006
Study Completion Date: May 2008
Primary Completion Date: April 2008 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with newly diagnosed, histologically confirmed primary lung cancer

Inclusion Criteria:

  • Histologically proven primary lung cancer
  • Newly diagnosed
  • No specific treatment given
  • No active infection in the previous week
  • No general anesthesia in the previous week

Exclusion Criteria:

  • Known adrenal disease
  • Receiving exogenous systemic corticosteroids
  • Concomitant illness known to affect adrenal function. e.g. active TB
  Contacts and Locations
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Please refer to this study by its identifier: NCT00364624

China, Hong Kong SAR
Department of Medicine, Princess Margaret Hospital
Kowloon, Hong Kong SAR, China
Sponsors and Collaborators
Princess Margaret Hospital, Hong Kong
Principal Investigator: Wai C YU, MBBS Princess Margaret Hospital, Hong Kong
  More Information

Responsible Party: Dr. W C Yu, Consultant Physician, Princess Margaret Hospital, Hong Kong Identifier: NCT00364624     History of Changes
Other Study ID Numbers: KW/FR/06-008
Study First Received: August 14, 2006
Last Updated: January 15, 2009

Keywords provided by Princess Margaret Hospital, Hong Kong:
lung cancer
adrenal insufficiency

Additional relevant MeSH terms:
Lung Neoplasms
Adrenal Insufficiency
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Lung Diseases
Respiratory Tract Diseases
Adrenal Gland Diseases
Endocrine System Diseases
Epinephryl borate
Adrenergic alpha-Agonists
Adrenergic Agonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Adrenergic beta-Agonists
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Anti-Asthmatic Agents
Respiratory System Agents
Vasoconstrictor Agents processed this record on May 25, 2017