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Adrenal Function in Patients With Newly Diagnosed Lung Cancer

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ClinicalTrials.gov Identifier: NCT00364624
Recruitment Status : Completed
First Posted : August 15, 2006
Last Update Posted : January 16, 2009
Sponsor:
Information provided by:

Study Description
Brief Summary:
Patients with newly diagnosed lung cancer may have hypofunction of the adrenal cortex either from tumour metastasis or other mechanisms. Since lung cancer patient may have to undergo stressful investigation and treatments, undetected hypofunction of the adrenal cortex may be hazardous. Knowledge of the size of the problem may help determine whether routine check is warranted.

Condition or disease
Lung Cancer Adrenal Insufficiency

Study Design

Study Type : Observational
Actual Enrollment : 133 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Adrenal Cortical Function in Patients With Newly Diagnosed Lung Cancer
Study Start Date : August 2006
Primary Completion Date : April 2008
Study Completion Date : May 2008


Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with newly diagnosed, histologically confirmed primary lung cancer
Criteria

Inclusion Criteria:

  • Histologically proven primary lung cancer
  • Newly diagnosed
  • No specific treatment given
  • No active infection in the previous week
  • No general anesthesia in the previous week

Exclusion Criteria:

  • Known adrenal disease
  • Receiving exogenous systemic corticosteroids
  • Concomitant illness known to affect adrenal function. e.g. active TB
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00364624


Locations
China, Hong Kong SAR
Department of Medicine, Princess Margaret Hospital
Kowloon, Hong Kong SAR, China
Sponsors and Collaborators
Princess Margaret Hospital, Hong Kong
Investigators
Principal Investigator: Wai C YU, MBBS Princess Margaret Hospital, Hong Kong
More Information

Responsible Party: Dr. W C Yu, Consultant Physician, Princess Margaret Hospital, Hong Kong
ClinicalTrials.gov Identifier: NCT00364624     History of Changes
Other Study ID Numbers: KW/FR/06-008
First Posted: August 15, 2006    Key Record Dates
Last Update Posted: January 16, 2009
Last Verified: January 2009

Keywords provided by Princess Margaret Hospital, Hong Kong:
lung cancer
adrenal insufficiency

Additional relevant MeSH terms:
Lung Neoplasms
Adrenal Insufficiency
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases
Adrenal Gland Diseases
Endocrine System Diseases
Epinephrine
Racepinephrine
Epinephryl borate
Adrenergic alpha-Agonists
Adrenergic Agonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Adrenergic beta-Agonists
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Anti-Asthmatic Agents
Respiratory System Agents
Mydriatics
Sympathomimetics
Vasoconstrictor Agents