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American Migraine Prevention Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2008 by Dynamic Health Resources.
Recruitment status was:  Recruiting
Information provided by:
Dynamic Health Resources Identifier:
First received: August 9, 2006
Last updated: April 22, 2008
Last verified: April 2008
The purpose of this study is to evaluate the use of nutritional supplementation and dietary management for the reduction in frequency, duration, and intensity of migraine headache pain.

Condition Intervention Phase
Migraine Disorders Behavioral: Serotona Plus and dietary behavior management Phase 4

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Nutritional Based Protocol to Balance Serotonin for the Prevention or Reduced Frequency/Duration/Intensity of Migraines

Resource links provided by NLM:

Further study details as provided by Dynamic Health Resources:

Primary Outcome Measures:
  • Migraine Impact and Disability Survey (MIDAS) - symptoms measured at study beginning and at 90 days

Estimated Enrollment: 1000
Study Start Date: January 2006
Estimated Study Completion Date: December 2008
Detailed Description:

AMPS, the American Migraine Prevention Study Program is a home based nutritional study for migraine prevention. It is designed to evaluate a nutritional supplement along with proper diet, and trigger management that may prevent migraines or reduce the frequency, duration and intensity of migraine headache pain.

The AMPS Program is availalbe nationwide. It is a home based study program.

During the three month study period, participants will be asked to take a daily nutritional supplement and follow a recommended diet to avoid potential migraine triggers. Participants will be asked to maintain a headache log and submit headache questionnaires at the beginning and end of the study. Participants do not have to travel and can participate from their current location.


Ages Eligible for Study:   18 Years to 72 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinical diagnosis of migraines
  • Ages 18-72
  • Migraines more than once per month
  • Diagnosed migraines for more than one year

Exclusion Criteria:

  • Pregnant/nursing
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00363506

Contact: John J Carvalho, MBA 757-721-7781
Contact: Katherine huffman, MA 571-334-9154

United States, Virginia
Nationwide home based study program Recruiting
Chesapeake, Virginia, United States, 23320
Contact: John J Carvalho, MBA    757-572-7781   
Contact: Katherine huffman, MA    571-334-9154   
Principal Investigator: Dr. John A Allocca, PhD, ScD         
Sponsors and Collaborators
Dynamic Health Resources
Study Chair: John J Carvalho, MBA Dynamic Health Resources
  More Information

Additional Information: Identifier: NCT00363506     History of Changes
Other Study ID Numbers: DHR-757962-7081
Study First Received: August 9, 2006
Last Updated: April 22, 2008

Keywords provided by Dynamic Health Resources:

Additional relevant MeSH terms:
Migraine Disorders
Headache Disorders, Primary
Headache Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases processed this record on September 21, 2017