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Cardiovascular Disease Risk Factors in Chinese American Immigrants (CHA-CHA)

This study has been completed.
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Judith Wylie-Rosett, Albert Einstein College of Medicine of Yeshiva University Identifier:
First received: August 8, 2006
Last updated: August 5, 2015
Last verified: August 2015
The Chinese population is currently the fastest growing ethnic group in New York City (NYC). Research has shown that Chinese immigrants living in NYC have higher rates of cardiovascular disease (CVD) than individuals in China. This study will evaluate the effect that acculturation has on health habits and CVD risk factors in Chinese immigrants living in NYC.

Cardiovascular Diseases
Diabetes Mellitus
Metabolic Syndrome X

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
Official Title: Chinese American Cardiovascular Health Assessment CHA-CHA

Resource links provided by NLM:

Further study details as provided by Albert Einstein College of Medicine, Inc.:

Primary Outcome Measures:
  • Number of Participants With Cardiovascular Risk Factors [ Time Frame: 4 years ]

Biospecimen Retention:   Samples With DNA
Biospecimens are being analyzed to evaluate the relationship between biomarker, behaviors and sociodemographic variables. Stored specimens will permit future analysis that may involve genetic variables related to biomarker findings.

Enrollment: 2072
Study Start Date: January 2007
Study Completion Date: October 2009
Primary Completion Date: July 2009 (Final data collection date for primary outcome measure)
Detailed Description:

CVD includes diseases that affect the heart and blood vessels. The underlying cause of CVD is atherosclerosis, in which fatty plaques develop on the inner walls of arteries. There are many risk factors for CVD, including inflammation, high blood pressure, high cholesterol, and obesity. Research has shown that CVD mortality rates differ greatly between Chinese immigrants living in NYC and individuals living in China. Because of this difference, it is important to understand the impact of immigration and acculturation on health habits and psychosocial factors, which may influence the development of CVD. This study will gather information from Chinese immigrants in NYC to identify the impact of immigration and acculturation on behavior and CVD risk factors. In addition, results from this study may provide insight into the CVD risk patterns in other immigrant groups.

This study will enroll Chinese immigrants living in NYC. Participants will attend one study visit and will complete questionnaires to assess their health habits (diet, physical activity, and smoking), stress levels, and socioeconomic status. Participants will also undergo a physical examination and blood collection.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Community sample from Chinatown region of NYC.

Inclusion Criteria:

  • Chinese immigrant
  • Currently residing in NYC
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00362128

United States, New York
New York Downtown Hospital
New York, New York, United States, 10038
Sponsors and Collaborators
Albert Einstein College of Medicine, Inc.
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Judith Wylie-Rosett, EdD Albert Einstein College of Medicine, Inc.
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Judith Wylie-Rosett, Principal Investigator, Albert Einstein College of Medicine of Yeshiva University Identifier: NCT00362128     History of Changes
Other Study ID Numbers: 1338
R01HL077809 ( US NIH Grant/Contract Award Number )
Study First Received: August 8, 2006
Results First Received: July 6, 2015
Last Updated: August 5, 2015

Keywords provided by Albert Einstein College of Medicine, Inc.:
Blood Pressure, High
Tobacco Use Disorder

Additional relevant MeSH terms:
Diabetes Mellitus
Cardiovascular Diseases
Metabolic Syndrome X
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Insulin Resistance
Hyperinsulinism processed this record on May 22, 2017