Comparison of Tramadol vs Remifentanyl Patient Controlled Analgesia for Second Trimester Abortions
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ClinicalTrials.gov Identifier: NCT00361686 |
Recruitment Status
:
Completed
First Posted
: August 8, 2006
Last Update Posted
: November 24, 2015
|
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Patients undergoing second trimester abortions will recieve either patient controlled analgesia with either remifentanyl or tramadol for pain alleviation.
We beleive both to be equally effective for pain alleviation.
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Abortion,Induced | Drug: tramadol Drug: remifentanyl Device: patient contolled analgesia | Not Applicable |
Women undergoing second trimester abortions will recieve patient controlled analgesia eith either tramadol or remifentanyl.
Patients will not know what they are recieving.
Patients in the tramadol goup will get a loading dose of tramadol and metocloparamide while the women in the remifentanyl group will be given a loading placebo.
Women will then be attached to one of the two patinet controlled analgesia protocols.
Throughout their laboring process they will be monitored for blood pressure, pulse, breathing rate, sedation score and nausea.
Additional medicatyion will be given for nausea.
If woman are still in pain the patient controlled analgesia settings will be set to deliver a higher dose. If the woman remains in pain, she will be given an additional per os medication.If this still does not alleviate pain, the option of epidural analgesia will be offered.
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 40 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double |
Primary Purpose: | Treatment |
Official Title: | Randomized Double Blind Study Comparing Patient Controlled Analgesia With Tramadol vs. Remifentanyl for Women Undergoing 2nd Trimester Abortions |
Study Start Date : | January 2006 |
Actual Primary Completion Date : | January 2007 |
Actual Study Completion Date : | January 2007 |
- Satisfaction
- VAS scores
- Nausea
- Sedation

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Ages Eligible for Study: | 18 Years to 50 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Woman undergoing 2nd trimester abortion -
Exclusion Criteria:
-
Seizure disorder
- * Psychiatric disorder
- Inability to recieve patient controlled analgesia
- Allergy to tramadol or remifentanyl

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00361686
Israel | |
Rabin Medical Center | |
Petach Tiqvah, Israel |
Study Director: | Sharon Orbach-Zinger | Rabin Medical Center |
ClinicalTrials.gov Identifier: | NCT00361686 History of Changes |
Other Study ID Numbers: |
3820 |
First Posted: | August 8, 2006 Key Record Dates |
Last Update Posted: | November 24, 2015 |
Last Verified: | July 2006 |
Keywords provided by Rabin Medical Center:
tramadol remifentanyl patient controlled analgesia abortion |
Additional relevant MeSH terms:
Tramadol Remifentanil Analgesics, Opioid Narcotics Central Nervous System Depressants Physiological Effects of Drugs Analgesics |
Sensory System Agents Peripheral Nervous System Agents Hypnotics and Sedatives Anesthetics, Intravenous Anesthetics, General Anesthetics |