Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study
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|ClinicalTrials.gov Identifier: NCT00361452|
Recruitment Status : Terminated
First Posted : August 8, 2006
Last Update Posted : August 8, 2006
|Condition or disease||Intervention/treatment||Phase|
|Rsv Bronchiolitis||Drug: nebulized epinephrine and nebulized albuterol||Phase 4|
Inpatient Infants younger than 2 years of age with first episode of RSV bronchiolitis will be randomly assigned to treatment with nebulized epinephrine (1 mg diluted with 3 ml of 0.9% saline) or nebulized albuterol (2.5 mg diluted with 3.5 ml of 0.9% saline). Both solutions will be provided in identical containers.
Clinical assessment and clinical score will be done before treatment, 10 and 30 minutes after treatment. The following parameters were recorded at each time point, wheezing, respiratory distress, O2 saturation, respiratory rate and heart rate. Computerized lung sounds as well, will be recorded before treatment, 10 and 30 minutes after treatment via 4 contact sensors attached to the chest.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||30 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study|
|Study Start Date :||December 2000|
|Study Completion Date :||May 2001|
- respiratory clinical score
- computerized quantification of wheezing and crackles
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00361452
|Pediatric Ward, Rambam Medical Centre|
|Haifa, Israel, 31096|
|Principal Investigator:||LEA BENTUR, MD||Rambam medical centre, pediatric pulmonary unit, HAIFA|