Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP.

This study has been completed.
Information provided by:
Regional Hospital Holstebro Identifier:
First received: August 3, 2006
Last updated: April 17, 2008
Last verified: April 2008
We wanted to test the hypothesis that treatment with continuous positive airway pressure reduces nocturnal hypoxia and thereby affecting levels of vasoactive hormones leading to a fall in blood pressure patients with obstructive sleep apnea.

Condition Intervention Phase
Obstructive Sleep Apnea
Device: Continuous Positive Airway Pressure
Phase 4

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label

Resource links provided by NLM:

Further study details as provided by Regional Hospital Holstebro:

Estimated Enrollment: 50
Study Start Date: February 2004
Estimated Study Completion Date: February 2005

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age between 20 and 65 years
  • Obstructive sleep apnea
  • Hypertension or normal blood pressure

Exclusion Criteria:

  • Drug or alcohol abuse
  • Pregnancy
  • History or clinical signs of disease in the heart, lungs, brain,liver, kidneys or endocrine organs
  • Diabetes
  Contacts and Locations
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Please refer to this study by its identifier: NCT00360659

Department of Medicine, Holstebro Hospital
Holstebro, Ringkoebing County, Denmark, 7500
Sponsors and Collaborators
Regional Hospital Holstebro
Study Chair: Erling B Pedersen, Professor Regional Hospital Holstebro
  More Information

No publications provided

Responsible Party: Pia H Gjørup, Department of Medical Research, Holstebro Hospital Identifier: NCT00360659     History of Changes
Other Study ID Numbers: MED.RES.HOS.2004.02.PHH
Study First Received: August 3, 2006
Last Updated: April 17, 2008
Health Authority: Denmark: The Danish National Committee on Biomedical Research Ethics

Keywords provided by Regional Hospital Holstebro:
Obstructive sleep Apnea
Vasoactive hormones

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Nervous System Diseases
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders
Sleep Disorders, Intrinsic processed this record on November 25, 2015