Efficacy of Homeopathic Nasal Formulation for Management of Experimental Rhinoviral Colds

Inclusion Criteria:

To be considered eligible for enrollment into this study, subject must:

1. Be healthy based on medical history, physical and nasal examination
2. Be male or non-pregnant, non-lactating female (women of child-bearing potential must be using an acceptable form of contraception, including abstinence, as determined by the Investigator)
3. Be between 18 - 60 years old
4. Be willing to refrain from taking nasal decongestants, antihistamines or cough/cold preparations (this includes dietary supplements and homeopathic preparations used specifically for cold/flu e.g., vitamin C, zinc, echinacea) within the 7 days prior to Day 0 and through Day 5
5. Be willing to refrain from taking any other medication (except contraceptive preparations, hormone replacement therapy, acne medication) within 2 days prior to Day 0 and through Day 5
6. Has read, signed and received a copy of the Informed Consent Form.

Exclusion Criteria:

Subjects will be excluded from the study if they:

1. Are intolerant of nasal sprays
2. Require a medication on regular basis (3 or more times/week) except contraceptive preparations, hormone replacement therapy, acne medication
3. Have a history of chronic diseases such as respiratory (e.g., chronic rhinitis, sinusitis, asthma, chronic bronchitis, pneumonia, persistent or chronic cough, emphysema, breathing problems, excessive phlegm or mucus), cardiovascular, endocrine, neurological, hepatic, gastrointestinal, renal, hematological, urological, immunological, ophthalmic diseases requiring medication
4. Have a history of headache (e.g., frequent migraines, cluster headaches, 3+ headaches/week)
5. Have had cold symptoms in the past 14 days
6. Are currently symptomatic with respiratory allergy
7. Have any clinically significant abnormalities of the upper (including history of nose bleeds, nasal abnormalities or other nasal pathology such as irreversible nasal mucosal hypertrophy or severe nasal septal deviation) or lower respiratory tract
8. Have used any investigational medication in the past 30 days
9. Are smokers
10. Have serum neutralizing antibody titer of >1 to RV16 at Pre-screening
11. Have a condition or is taking a medication that the Investigator and/or designee believes could jeopardize the safety of the subject, would interfere with the evaluation or confound the interpretation of the study results
12. Have positive urine pregnancy test (for female subjects only)