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Effects of Nerve Block on Knee Function After Knee Replacement

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00358241
Recruitment Status : Withdrawn (PI left JHU and is not able to be reached for updates)
First Posted : July 31, 2006
Last Update Posted : May 18, 2020
Sponsor:
Information provided by (Responsible Party):
Johns Hopkins University

Brief Summary:
Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine. Another method is to use a "nerve block" which involves placing a thin catheter (tube) into the lower back near the nerves that sense pain in the knee and give a local anesthetic to numb the nerves. Sometimes both methods are used together. This research is being done to determine whether nerve blocks with a local anesthetic improve knee recovery in addition to providing pain relief as compared to IV pain medicine alone

Condition or disease Intervention/treatment Phase
Postoperative Pain Procedure: Nerve block Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Official Title: Effects of Continuous Lumbar Plexus Nerve Block on Functional Restoration and Outcome After Unilateral Total Knee Arthroplasty




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Ages Eligible for Study:   21 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Age 21-80 year old
  • ASA Physical Status ASA I and II
  • Mentally competent
  • Intellectually competent
  • Body mass index <35
  • No severe cardiac diseases
  • No severe pulmonary diseases
  • Unilateral knee disease
  • No other lower extremity joint disease
  • No chronic narcotic therapy or illicit drug use

Exclusion Criteria:

  • Age <21 or >80 year old
  • ASA Physical Status >ASA II
  • Mentally incompetent
  • Intellectually incompetent or cognitively impaired
  • Non-English speaking patient
  • Worker's compensation patient
  • Body mass index > 35
  • Bilateral knee disease
  • Has other lower extremity joint disease
  • Severe cardiac diseases
  • Severe pulmonary diseases
  • Chronic narcotic therapy or illicit drug use
  • Pregnancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00358241


Locations
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United States, Maryland
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States, 21224
Sponsors and Collaborators
Johns Hopkins University
Investigators
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Principal Investigator: J Hang, MD, PhD Johns Hopkins Medicine, Johns Hopkins University
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Responsible Party: Johns Hopkins University
ClinicalTrials.gov Identifier: NCT00358241    
Other Study ID Numbers: 04-03-05-05
First Posted: July 31, 2006    Key Record Dates
Last Update Posted: May 18, 2020
Last Verified: May 2019
Keywords provided by Johns Hopkins University:
Nerve block, postoperative pain, analgesia
Additional relevant MeSH terms:
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Pain, Postoperative
Postoperative Complications
Pathologic Processes
Pain
Neurologic Manifestations
Signs and Symptoms