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Effects of Nerve Block on Knee Function After Knee Replacement

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2006 by Johns Hopkins University.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00358241
First Posted: July 31, 2006
Last Update Posted: July 31, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Johns Hopkins University
  Purpose
Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine. Another method is to use a “nerve block” which involves placing a thin catheter (tube) into the lower back near the nerves that sense pain in the knee and give a local anesthetic to numb the nerves. Sometimes both methods are used together. This research is being done to determine whether nerve blocks with a local anesthetic improve knee recovery in addition to providing pain relief as compared to IV pain medicine alone

Condition Intervention
Postoperative Pain Procedure: Nerve block

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Official Title: Effects of Continuous Lumbar Plexus Nerve Block on Functional Restoration and Outcome After Unilateral Total Knee Arthroplasty

Further study details as provided by Johns Hopkins University:

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Age 21-80 year old
  • ASA Physical Status ASA I and II
  • Mentally competent
  • Intellectually competent
  • Body mass index <35
  • No severe cardiac diseases
  • No severe pulmonary diseases
  • Unilateral knee disease
  • No other lower extremity joint disease
  • No chronic narcotic therapy or illicit drug use

Exclusion Criteria:

  • Age <21 or >80 year old
  • ASA Physical Status >ASA II
  • Mentally incompetent
  • Intellectually incompetent or cognitively impaired
  • Non-English speaking patient
  • Worker’s compensation patient
  • Body mass index > 35
  • Bilateral knee disease
  • Has other lower extremity joint disease
  • Severe cardiac diseases
  • Severe pulmonary diseases
  • Chronic narcotic therapy or illicit drug use
  • Pregnancy
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00358241


Contacts
Contact: A. Rollingson 410-550-0942

Locations
United States, Maryland
Johns Hopkins Bayview Medical Center Recruiting
Baltimore, Maryland, United States, 21224
Contact: A Rollingson    410-550-0942      
Sponsors and Collaborators
Johns Hopkins University
Investigators
Principal Investigator: J Hang, MD, PhD Johns Hopkins Medicine, Johns Hopkins University
  More Information

ClinicalTrials.gov Identifier: NCT00358241     History of Changes
Other Study ID Numbers: 04-03-05-05
First Submitted: July 27, 2006
First Posted: July 31, 2006
Last Update Posted: July 31, 2006
Last Verified: July 2006

Keywords provided by Johns Hopkins University:
Nerve block, postoperative pain, analgesia

Additional relevant MeSH terms:
Pain, Postoperative
Pain
Neurologic Manifestations
Nervous System Diseases
Postoperative Complications
Pathologic Processes
Signs and Symptoms