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Recovery of Hand Function Through Mental Practice.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00355836
Recruitment Status : Completed
First Posted : July 25, 2006
Last Update Posted : November 5, 2015
Chief Scientist Office of the Scottish Government
Information provided by:
University of Aberdeen

Brief Summary:
The purpose of this study is to assess the therapeutic benefits of motor imagery training in stroke patients with persistent motor weakness.

Condition or disease Intervention/treatment Phase
Stroke Behavioral: Mental Imagery Not Applicable

Detailed Description:

Stroke is a common and highly debilitating illness. Many patients (41-45%) experience chronic motor impairments (Dijkerman et al., 1996) and limitations in activities of daily living (Wade & Langton Hewer, 1987) even after extensive neurological rehabilitation. They often result in long-term dependence at a considerable cost to the carers and the health service. It is therefore crucial to optimise motor recovery after stroke. This study investigates the therapeutic benefits of motor imagery training in stroke patients with a motor weakness.

Evidence for the idea that motor imagery training could enhance the recovery of hand function comes from several separate bases of evidence: the sports literature; neurophysiological evidence; evidence from health psychology research; as well as preliminary findings using motor imagery techniques in stroke patients.

There is evidence to suggest that mental rehearsal of movement can produce effects normally attributed to practising the actual movements. Imagining hand movements could stimulate the redistribution of brain activity, which accompanies recovery of hand function, thus resulting in a reduced motor deficit. Patients are assessed before and after a four-week evaluation period. In this randomised controlled trial 45 patients daily mentally rehearse movements with their affected hand under close supervision. Their recovery is compared to 45 patients who perform closely supervised non-motor mental rehearsal, and 45 patients who are not engaged in a training program.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 135 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Can Motor Imagery Enhance Recovery of Hand Function After Stroke? Evaluation of Motor Imagery Training.
Study Start Date : November 2004
Actual Primary Completion Date : February 2007
Actual Study Completion Date : February 2007

Primary Outcome Measures :
  1. Action Research Arm Test (ARAT) (Lyle, 1981)

Secondary Outcome Measures :
  1. Grip strength (dynamometer; Heller et al., 1987),
  2. Nine hole pegboard task (Mathiowetz et al., 1985, Wade [ref]),
  3. Function Limitation Profile
  4. Barthel Index
  5. Recovery Locus of Control

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Confirmed diagnosis of stroke in the last 1-6 months Persisting upper limb weakness -

Exclusion Criteria:

Alcohol/ Drug abuse Psychiatric history Previous illness that has impacted on individuals Activity of Daily living

- Dementia (assessed by MSQ) Severe Aphasia

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00355836

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United Kingdom
University of Aberdeen
Aberdeen, United Kingdom, AB24 3FX
Ninewells Hospital
Dundee, United Kingdom
Sponsors and Collaborators
University of Aberdeen
Chief Scientist Office of the Scottish Government
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Principal Investigator: Marie Johnston, Prof University of Aberdeen
Layout table for additonal information Identifier: NCT00355836    
Other Study ID Numbers: CZH/4/153
First Posted: July 25, 2006    Key Record Dates
Last Update Posted: November 5, 2015
Last Verified: November 2015
Keywords provided by University of Aberdeen:
Motor Imagery
health psychology
randomised controlled trial
Additional relevant MeSH terms:
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Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases