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BNP Guided Care in Addition to Multidisciplinary Care

This study has been terminated.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00355017
First Posted: July 20, 2006
Last Update Posted: October 18, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Medical University of Vienna
  Purpose

HF is associated with repeated hospitalisations and poor prognosis.The aim of this study is to investigate whether BNP-guided care (BGC) in addition to multidisciplinary management(MM) improves outcome compared to HNC alone or usual care (UC) for decompensated HF patients after discharge.

Patients hospitalised with cardiac decompensation in 9 Viennese hospitals are randomised to BGC, MM alone, or UC. MM includes 2 consultations of a heart failure (HF) specialist 10 days and 2 months after discharge for recommending medical optimisation and care by a specialised HF nurse including 4 home visits and telephone contact. In addition, BGC includes intensified increase of medical treatment during repeated follow-up visits in a HF clinic in patients with an Nt-BNP level above 2200pg/ml at discharge.


Condition Intervention
Decompensated Heart Failure Procedure: BNP-guided care in addition to multidisciplinary management

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Official Title: NT-BNP Guided Care in Addition to Multidisciplinary Care in Patients With Chronic Heart Failure A Three-Arm, Prospective, Randomised Study

Resource links provided by NLM:


Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Heart failure rehospitalisation rate;
  • combined endpoint death or heart failure rehospitalisation;

Study Start Date: September 2003
Estimated Study Completion Date: September 2005
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Clinical signs and symptoms of cardiac decompensation during the present hospitalisation
  2. NYHA class III or IV at time of admission
  3. Cardiothoracic ratio > 0.5, and/or left ventricular ejection fraction <40% documented by echocardiography

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00355017


Sponsors and Collaborators
Medical University of Vienna
Investigators
Principal Investigator: Richard Pacher, MD Medical University of Vienna
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00355017     History of Changes
Other Study ID Numbers: VF: 05.05.2003
First Submitted: July 19, 2006
First Posted: July 20, 2006
Last Update Posted: October 18, 2006
Last Verified: July 2006

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases