Arterial Stiffness, Wave Reflections and Renal Failure
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|ClinicalTrials.gov Identifier: NCT00354588|
Recruitment Status : Completed
First Posted : July 20, 2006
Last Update Posted : November 4, 2010
- Cardiovascular risk is high in patients with renal failure.
- Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
- In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
- Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure
|Condition or disease|
|Chronic Renal Failure Arterial Stiffness Arterial Wave Reflections|
|Study Type :||Observational|
|Actual Enrollment :||115 participants|
|Official Title:||Observational Study on the Prognostic Significance (Renal and Cardiovascular) of Arterial Stiffness and Arterial Wave Reflections in Patients With Mild to Moderate Renal Impairment|
|Study Start Date :||January 2006|
|Primary Completion Date :||October 2010|
|Study Completion Date :||October 2010|
- renal endpointdoubling serum creatinine, need for dialysis, renal transplantation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00354588
|Cardiology and Nephrology Department Klinikum Wels|
|Wels, Austria, 4600|
|Principal Investigator:||Thomas Weber, MD||Cardiology Department, Klinikum Wels, Austria|
|Principal Investigator:||Manfred Wallner, MD||Nephrology Department, Klinikum Wels, Austria|