Investigating Cytokine Genes of Stem Cell Donors
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|ClinicalTrials.gov Identifier: NCT00353821|
Recruitment Status : Completed
First Posted : July 19, 2006
Last Update Posted : September 13, 2018
This study seeks to investigate the factors that may account for the differences in the way a stem cell recipient s immune system works after a transplant. It will focus on cytokine genes, which give specific instructions to the genes and which may influence immune system response. More specifically, the purpose of the study is to find out how gene polymorphisms (gene variations among the population) affect the success or failure of a stem cell transplant.
Study participants will have donated blood for a stem cell transplant. They will be asked to give consent for NIH personnel to run special tests on these blood samples, which will have been placed in storage. It is hoped that blood samples will be studied from 600 stem cell donors.
|Condition or disease|
|Stem Cell Transplantation|
|Study Type :||Observational|
|Actual Enrollment :||24 participants|
|Official Title:||Cytokine Gene Polymorphisms in Allotransplant Donors|
|Study Start Date :||June 5, 2003|
|Study Completion Date :||March 2, 2018|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00353821
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Principal Investigator:||A. John Barrett, M.D.||National Heart, Lung, and Blood Institute (NHLBI)|