Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2)
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Direct Factor Xa Inhibitor YM150 for Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement.---A Double Blind, Parallel, Dose-finding Study in Comparison With Open Label Enoxaparin
Study Start Date
Primary Completion Date
Study Completion Date
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Scheduled for elective primary hip replacement
Age 18 years or over
Written informed consent obtained
Documented history or considered at increased risk of venous thromboembolism
Subjects considered at increased risk of bleeding
Surgery planned for contralateral hip at the same time or within 10 weeks after enrolment
Concomitant use of anticoagulants/ antiplatelet agents