Help guide our efforts to modernize
Send us your comments by March 14, 2020. Menu

Detection of Pulmonary Embolism With CECT

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00351754
Recruitment Status : Completed
First Posted : July 13, 2006
Last Update Posted : January 7, 2008
Information provided by:
Bracco Diagnostics, Inc

Brief Summary:
To compare the vascular enhancement of the two contrast agents in pulmonary Multi-detector CTA

Condition or disease Intervention/treatment Phase
Pulmonary Embolism Drug: Isovue Phase 4

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Enrollment : 120 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Diagnostic
Official Title: Detection of Pulmonary Embolism Comparing Isovue-370 and Visipaque 320 Using 64-Slice Multi-Detector Computed Tomographic Angiography
Study Start Date : July 2006
Actual Study Completion Date : November 2006

Resource links provided by the National Library of Medicine

Drug Information available for: Iopamidol

Primary Outcome Measures :
  1. Hounsfield Units (HU) measured at various levels of pulmonary arteries

Secondary Outcome Measures :
  1. Presence of artifacts; global enhancement

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients 18 yrs or older
  • With suspected PE
  • Referred for MDCTA of pulmonary arteries
  • Signed informed consent

Exclusion Criteria:

  • Pregnant and lactating females
  • History of hypersensitivity to iodinated contrast agents
  • Hyperthyroidism or pheochromocytoma
  • Severe CHF
  • Renal impairment
  • Weight greater than 300 lbs
  • Pacemaker
  • Swan Ganz catheter
  • Defibrillator or other intrathoracic metallic vascular device
  • Received an investigational compound within 30 days of being in the study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00351754

Layout table for location information
United States, New Jersey
Bracco Diagnostics, Inc.
Princeton, New Jersey, United States, 08540
Sponsors and Collaborators
Bracco Diagnostics, Inc
Layout table for investigator information
Study Director: Steve Sireci, M.D. Bracco Diagnostics

Layout table for additonal information Identifier: NCT00351754    
Other Study ID Numbers: IOP 106
First Posted: July 13, 2006    Key Record Dates
Last Update Posted: January 7, 2008
Last Verified: January 2008
Additional relevant MeSH terms:
Layout table for MeSH terms
Pulmonary Embolism
Embolism and Thrombosis
Vascular Diseases
Cardiovascular Diseases
Lung Diseases
Respiratory Tract Diseases