Myoma Microvascularization Analysis Using Sonovue Before and After Uterine Artery Embolization
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|ClinicalTrials.gov Identifier: NCT00351494|
Recruitment Status : Unknown
Verified November 2007 by University Hospital, Tours.
Recruitment status was: Recruiting
First Posted : July 13, 2006
Last Update Posted : November 22, 2007
|Condition or disease||Intervention/treatment|
|Myoma||Procedure: contrast enhanced ultrasonography Procedure: embolization|
Before embolization of the uterine artery, 40 patients with unique or multiple myomas will be included prospectively in our study and evaluated with sonography before and after injection of Sonovue (2.4 ml) (Bracco Int Milano Italy). Pelvic ultrasound with contrast enhancement will be done the day after and six months after the procedure.
Microvascularization of the myomas and the endometrium will be described. Some tiny myomas which are not visible on conventional sonography could be identified for a perfect matching with MRI detection.
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||Myoma Microvascularization Analysis Using Sonovue Before and After Uterine Artery Embolization|
|Study Start Date :||July 2006|
|Estimated Study Completion Date :||June 2009|
Procedure: contrast enhanced ultrasonography
Three contrast-enhanced ultrasonography : before embolization, after one day and after 6 months.
Abdominal route 2.4 ml sonovue per injection / bolus
- To investigate the usefulness of contrast-enhanced ultrasound with real-time imaging technique in the assessment of vascular patterns from myomas myometrium and ovaries before and after uterine artery embolization [ Time Frame: Inclusion period and follow-up ]
- Accordance between contrast-enhanced imaging and IRM [ Time Frame: inclusion period and follow-up ]
- Accordance between early vascular patterns due to embolization of the fibroma and the success of the technique which is evaluated after 6 month [ Time Frame: inclusion period and follow-up ]
- Relationship between the post embolization pain and the vascular change of the fibroma and the myometrium [ Time Frame: inclusion period ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00351494
|Contact: Henri MARRET, Pr||(33) 2 47 47 82 email@example.com|
|Contact: Catherine ROUSSEL, ARC||(33) 2 47 47 97 firstname.lastname@example.org|
|Centre d'Innovation Technologique-Ultrasons||Recruiting|
|Tours, France, 37344|
|Contact: Henri MARRET, Pr (33) 2 47 47 82 59 email@example.com|
|Contact: Catherine ROUSSEL, ARC (33) 2 47 47 97 89 firstname.lastname@example.org|
|Sub-Investigator: François TRANQUART, Pr|
|Sub-Investigator: Aurore BLEUZEN, MD|
|Sub-Investigator: Denis HERBRETEAU, Pr|
|Sub-Investigator: Marc LEGEAIS, MD|
|Sub-Investigator: Nathalie WAGNER, MD|
|Principal Investigator:||Henri MARRET, Pr||Service de Gynécologie Obstétrique CHRU TOURS|
|Study Director:||François TRANQUART, Pr||Centre d'Innovation Technologique CHRU TOURS|