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BBC ONE - British Bifurcation Coronary Study (BBC ONE)

This study has been completed.
Information provided by:
Royal Sussex County Hospital Identifier:
First received: July 11, 2006
Last updated: April 15, 2008
Last verified: March 2008
The study aims to assess whether a SIMPLE or a COMPLEX strategy is best for the treatment of coronary bifurcation stenoses.

Condition Intervention Phase
Ischaemic Heart Diseases Stenosis Angina Procedure: Coronary Angioplasty Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: British Bifurcation Coronary Study - Old, New and Evolving Strategies.

Further study details as provided by Royal Sussex County Hospital:

Primary Outcome Measures:
  • Death
  • Myocardial infarction
  • Target vessel revascularisation

Secondary Outcome Measures:
  • Repeat angiography
  • Stent thrombosis

Enrollment: 500
Study Start Date: January 2005
Study Completion Date: December 2007
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Detailed Description:
500 patients will be randomised to either a SIMPLE strategy (provisional T stenting) or a COMPLEX strategy (crush or culotte stenting) with clinical follow-up at 9 months.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:>18 years

  • Coronary Bifurcation Lesion requiring treatment

Exclusion Criteria:

  • Cardiogenic Shock
  • Acute MI
  • Additional type C lesion for Rx platelets <50
  • LVEF <20%
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00351260

United Kingdom
Royal Sussex County Hospital
Brighton, United Kingdom, BN2 5BE
Sponsors and Collaborators
Royal Sussex County Hospital
Principal Investigator: David J.R, Hildick-Smith, MD Royal Sussex County Hospital
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00351260     History of Changes
Other Study ID Numbers: COREC2006
Study First Received: July 11, 2006
Last Updated: April 15, 2008

Keywords provided by Royal Sussex County Hospital:
drug elution

Additional relevant MeSH terms:
Heart Diseases
Myocardial Ischemia
Coronary Artery Disease
Cardiovascular Diseases
Vascular Diseases
Coronary Disease
Arterial Occlusive Diseases processed this record on September 19, 2017