BBC ONE - British Bifurcation Coronary Study (BBC ONE)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00351260
Recruitment Status : Completed
First Posted : July 12, 2006
Last Update Posted : April 16, 2008
Information provided by:
Royal Sussex County Hospital

Brief Summary:
The study aims to assess whether a SIMPLE or a COMPLEX strategy is best for the treatment of coronary bifurcation stenoses.

Condition or disease Intervention/treatment Phase
Ischaemic Heart Diseases Stenosis Angina Procedure: Coronary Angioplasty Phase 3

Detailed Description:
500 patients will be randomised to either a SIMPLE strategy (provisional T stenting) or a COMPLEX strategy (crush or culotte stenting) with clinical follow-up at 9 months.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 500 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: British Bifurcation Coronary Study - Old, New and Evolving Strategies.
Study Start Date : January 2005
Actual Primary Completion Date : December 2007
Actual Study Completion Date : December 2007

Primary Outcome Measures :
  1. Death
  2. Myocardial infarction
  3. Target vessel revascularisation

Secondary Outcome Measures :
  1. Repeat angiography
  2. Stent thrombosis

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:>18 years

  • Coronary Bifurcation Lesion requiring treatment

Exclusion Criteria:

  • Cardiogenic Shock
  • Acute MI
  • Additional type C lesion for Rx platelets <50
  • LVEF <20%

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00351260

United Kingdom
Royal Sussex County Hospital
Brighton, United Kingdom, BN2 5BE
Sponsors and Collaborators
Royal Sussex County Hospital
Principal Investigator: David J.R, Hildick-Smith, MD Royal Sussex County Hospital

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00351260     History of Changes
Other Study ID Numbers: COREC2006
First Posted: July 12, 2006    Key Record Dates
Last Update Posted: April 16, 2008
Last Verified: March 2008

Keywords provided by Royal Sussex County Hospital:
drug elution

Additional relevant MeSH terms:
Heart Diseases
Myocardial Ischemia
Coronary Artery Disease
Cardiovascular Diseases
Vascular Diseases
Coronary Disease
Arterial Occlusive Diseases