The Microbiological Spectrum in Acute Dacryocystitis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00349297
Recruitment Status : Completed
First Posted : July 6, 2006
Last Update Posted : May 12, 2010
Information provided by:
Singapore National Eye Centre

Brief Summary:

Acute dacryocystitis in adults can be a very painful disease and may not respond well to medical therapy.

The purpose of this prospective non-randomised study is to determine the microorganisms causing acute dacryocystitis and the antibiotic sensitivities of these organisms.

The study also aims to correlate the microbiological findings to the severity of clinical manifestations and evaluate the effectiveness of our current practice of aspiration and empiric systemic antibiotic therapy in treating patients with acute dacryocystitis and hence review whether there is a need to alter current management strategy.

Condition or disease

Study Type : Observational
Time Perspective: Prospective
Study Start Date : November 2003
Actual Primary Completion Date : May 2008
Actual Study Completion Date : May 2008

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Acute dacryocystitis patients


  • Painful localised fluctuant induration just inferior to the medial canthal tendon of less than 2 weeks duration.


  • Non-fluctuant lacrimal sac swelling
  • Uncooperative patient
  • Unwilling Patient

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00349297

Singapore National Eye Centre
Singapore, Singapore, 168751
Sponsors and Collaborators
Singapore National Eye Centre
Principal Investigator: Anshu Arundhati, MRCSED, MMED Singapore National Eye Centre Identifier: NCT00349297     History of Changes
Other Study ID Numbers: R325/18/2003
First Posted: July 6, 2006    Key Record Dates
Last Update Posted: May 12, 2010
Last Verified: May 2010

Additional relevant MeSH terms:
Lacrimal Apparatus Diseases
Eye Diseases