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Does Undercorrection of Myopia Retard Myopia Progression Among Kindergarten Children?

This study has been withdrawn prior to enrollment.
(Stringent eligibility criterion caused difficulties in recruiting patients.)
Information provided by:
KK Women's and Children's Hospital Identifier:
First received: July 3, 2006
Last updated: October 3, 2011
Last verified: October 2011
The purpose of this study is to find out if undercorrection of myopia slow down the progression of myopia in kindergarten children.

Condition Intervention Phase
Refractive Error - Myopia
Drug: cyclopentolate
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double-Blind
Official Title: Does Undercorrection of Myopia Retard Myopia Progression Among Kindergarten

Resource links provided by NLM:

Further study details as provided by KK Women's and Children's Hospital:

Estimated Enrollment: 180
Study Start Date: December 2005
Study Completion Date: June 2008
Primary Completion Date: June 2008 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   5 Years to 6 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Children of chinese descent aged 5 - 6yrs
  2. Refractive error of -1.00 to -3.00Ds
  3. Less than 1.50 astigmatism in each eye. (No oblique axis)
  4. Visual acuity is 6/6 or better in both eyes.
  5. No binocular problems, no anisometropia >1.50D
  6. Will be staying in S'pore for at least 2 years.

Exclusion Criteria:

  Contacts and Locations
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Please refer to this study by its identifier: NCT00348166

Sponsors and Collaborators
KK Women's and Children's Hospital
Principal Investigator: Quah Boon Long Singapore National Eye Centre
  More Information Identifier: NCT00348166     History of Changes
Other Study ID Numbers: RAU/085/2005
Study First Received: July 3, 2006
Last Updated: October 3, 2011

Additional relevant MeSH terms:
Refractive Errors
Eye Diseases
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Muscarinic Antagonists
Cholinergic Antagonists
Cholinergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action processed this record on April 28, 2017