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Echocardiographic Assessment of Intrapulmonary Vasodilatation: Agitated Saline Versus Polygeline

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ClinicalTrials.gov Identifier: NCT00343122
Recruitment Status : Unknown
Verified September 2007 by Medical University of Vienna.
Recruitment status was:  Recruiting
First Posted : June 22, 2006
Last Update Posted : September 17, 2007
Sponsor:
Information provided by:
Medical University of Vienna

Brief Summary:
The purpose of the study is to evaluate agitated saline versus polygeline for detection of intrapulmonary vasodilatation in patients with cirrhosis.

Condition or disease Intervention/treatment
Liver Cirrhosis Procedure: echocardiography for intrapulmonary vasodilatation

Detailed Description:
Intrapulmonary vasodilatation is a frequent finding in patients with cirrhosis. Its diagnosis is established via contrast enhanced echocardiography. One used method is the contrast agent agitated saline and another frequently used method is the contrast agent polygeline. The purpose of this study is to compare these two echocardiographic contrast agents with respect to their ability to detect intrapulmonary vasodilatation.

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Evaluation of Two Methods for the Echocardiographic Assessment of Intrapulmonary Vasodilatation in Patients With Liver Cirrhosis: Agitated Saline Versus Polygelatine
Study Start Date : June 2006






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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • age > 18 years
  • presence of liver cirrhosis
  • evaluation for liver transplantation or transjugular intrahepatic portosystemic shunt

Exclusion Criteria:

  • inadequate echocardiographic image quality
  • allergies to echocardiographic contrast agents
  • pulmonary valve stenosis
  • pulmonary embolism
  • relevant tricuspid regurgitation
  • cardiomyopathy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00343122


Contacts
Contact: Valentin Fuhrmann, MD 0043-1-40400 ext 4766 valentin.fuhrmann@meduniwien.ac.at
Contact: Peter Schenk, MD 0043-1-40400 ext 4766

Locations
Austria
Intensive Care Unit 13H1, Dep. of Internal Medicine IV, Medical University of Vienna Recruiting
Vienna, Austria, A-1090
Contact: Valentin Fuhrmann, MD    0043-1-40400 ext 4766    valentin.fuhrmann@meduniwien.ac.at   
Principal Investigator: Peter Schenk, MD         
Sub-Investigator: Valentin Fuhrmann, MD         
Sponsors and Collaborators
Medical University of Vienna
Investigators
Principal Investigator: Peter Schenk, MD Intensive Care Unit 13h1, Dep. of Internal Medicine IV, Medical University of Vienna

Publications:
ClinicalTrials.gov Identifier: NCT00343122     History of Changes
Other Study ID Numbers: EK 4462005
First Posted: June 22, 2006    Key Record Dates
Last Update Posted: September 17, 2007
Last Verified: September 2007

Keywords provided by Medical University of Vienna:
liver
cirrhosis
hepatopulmonary syndrome

Additional relevant MeSH terms:
Fibrosis
Liver Cirrhosis
Pathologic Processes
Liver Diseases
Digestive System Diseases