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Functional Neuroimaging in Depression: Longitudinal Study of PET Metabolism in Correlation With Changes in Attentional Bias, Autobiographical Memory, Future Fluency and Facial Recognition in Depressed Patients Treated With Escitalopram.
Study Start Date
Primary Completion Date
Study Completion Date
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Ages Eligible for Study:
18 Years to 65 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Major Depression, Depressive episode, following DSM-IV criteria
MADRS-score > 25
Age: 18-65 yrs
Medication-free or anti-depressant wash-out 7 days (for fluoxetine: 6 weeks)
Lorazepam 1mg or zolpidem 10mg are allowed
Bipolar disorder, following DSM-IV criteria
Personality disorder, following DSM-IV criteria
Cognitive dysfunction due to trauma capitis or dementia
Women without contraceptive protection, with pregnancy or breast feeding
Pharmacological treatment or ingestion of substance that can influence cerebral perfusion less than a month before inclusion