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Endothelial Function as a Marker for Blood Pressure Control Among Hypertensive Diabetic Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00337038
First Posted: June 15, 2006
Last Update Posted: June 22, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Valentin Yurkevich, Soroka University Medical Center
  Purpose
Our aim is to examine the influence of blood pressure and glycemic control together with N-acetylcystein utilization on the endothelia function of hypertensive diabetic patient.The study population will include 50 diabetic patient with uncontrolled hypertention that will be recruited from the Hypertension Clinic of Soroka University Medical Center.

Condition Intervention Phase
Hypertension Diabetes Mellitus Type 2 Drug: N-acetylcystein(drug) Early Phase 1

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic

Resource links provided by NLM:


Further study details as provided by Valentin Yurkevich, Soroka University Medical Center:

Primary Outcome Measures:
  • endothelial function [ Time Frame: half of year ]

Secondary Outcome Measures:
  • blood pressure and glycemic control [ Time Frame: half of year ]

Enrollment: 50
Study Start Date: June 2006
Study Completion Date: July 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Drug: N-acetylcystein(drug)
    p.O t.Siran 200mg x1 during one weak
    Other Name: siran
  Eligibility

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diabetic patients with uncontrolled hypertension that will be recruited from the Hypertension Clinic of Soroka University Medical Center

Exclusion Criteria:

  • Pregnancy,secondary hypertention,malignancy or other serious illness
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00337038


Sponsors and Collaborators
Soroka University Medical Center
Investigators
Principal Investigator: Ester Paran, MD Hypertension Clinic of Soroka University Medical Center
Principal Investigator: Ester Paran, MD Soroka University Medical Center
  More Information

Responsible Party: Valentin Yurkevich, Dr Yurkevich, Soroka University Medical Center
ClinicalTrials.gov Identifier: NCT00337038     History of Changes
Other Study ID Numbers: sor431706ctil
First Submitted: June 14, 2006
First Posted: June 15, 2006
Last Update Posted: June 22, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases