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Endothelial Function as a Marker for Blood Pressure Control Among Hypertensive Diabetic Patients

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ClinicalTrials.gov Identifier: NCT00337038
Recruitment Status : Completed
First Posted : June 15, 2006
Last Update Posted : June 22, 2012
Sponsor:
Information provided by (Responsible Party):
Valentin Yurkevich, Soroka University Medical Center

Brief Summary:
Our aim is to examine the influence of blood pressure and glycemic control together with N-acetylcystein utilization on the endothelia function of hypertensive diabetic patient.The study population will include 50 diabetic patient with uncontrolled hypertention that will be recruited from the Hypertension Clinic of Soroka University Medical Center.

Condition or disease Intervention/treatment Phase
Hypertension Diabetes Mellitus Type 2 Drug: N-acetylcystein(drug) Early Phase 1

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 50 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Study Start Date : June 2006
Actual Primary Completion Date : July 2010
Actual Study Completion Date : July 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources


Intervention Details:
    Drug: N-acetylcystein(drug)
    p.O t.Siran 200mg x1 during one weak
    Other Name: siran


Primary Outcome Measures :
  1. endothelial function [ Time Frame: half of year ]

Secondary Outcome Measures :
  1. blood pressure and glycemic control [ Time Frame: half of year ]


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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diabetic patients with uncontrolled hypertension that will be recruited from the Hypertension Clinic of Soroka University Medical Center

Exclusion Criteria:

  • Pregnancy,secondary hypertention,malignancy or other serious illness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00337038


Sponsors and Collaborators
Soroka University Medical Center
Investigators
Principal Investigator: Ester Paran, MD Hypertension Clinic of Soroka University Medical Center
Principal Investigator: Ester Paran, MD Soroka University Medical Center

Responsible Party: Valentin Yurkevich, Dr Yurkevich, Soroka University Medical Center
ClinicalTrials.gov Identifier: NCT00337038     History of Changes
Other Study ID Numbers: sor431706ctil
First Posted: June 15, 2006    Key Record Dates
Last Update Posted: June 22, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases