MRSA Colonization in Peripartum Women and Their Offspring

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00336427
Recruitment Status : Completed
First Posted : June 13, 2006
Last Update Posted : June 13, 2006
Information provided by:
Orlando Regional Medical Center

Brief Summary:
We hypothesize that pregnant women are at baseline risk for carrying community-acquired MRSA, but also have frequent contact with healthcare workers which may put them at risk for hospital-acquired MRSA carriage. Our study aimed to identify the colonization rate of women in active labor and whether transmission to infants may occur.

Condition or disease
Pregnancy Bacterial Colonization

Detailed Description:
Mothers are at risk for carrying MRSA. What this risk is is not known. We have seen a dramatic increase in neonatal intensive care unit MRSA infections. Could mothers transmit MRSA to their newborns if they are asymptomatic carriers? Mothers come into close contact with health care providers, often have other children in daycare (known risk factor) and may have other exposures to MRSA. Our study was designed to sample 300 mother-infant pairs to determine whether MRSA carriage is present in asymptomatic women. The study consisted of obtaining informed consent, then performing a sterile swab of mothers' nares and vaginal area, then babies' nares and umbilicus once the baby was born.

Study Type : Observational
Enrollment : 600 participants
Allocation: Random Sample
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: A Prospective Study of MRSA Colonization in Peripartum Women and Their Offspring
Study Start Date : September 2005
Study Completion Date : May 2006

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Singleton pregnancy expected to deliver next 24 hours

Exclusion Criteria:

  • Cesarean sections

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00336427

Sponsors and Collaborators
Orlando Regional Medical Center
Principal Investigator: Margret G Reusch, MD ORMC Identifier: NCT00336427     History of Changes
Other Study ID Numbers: ORMC-MRSA-Pregnancy
First Posted: June 13, 2006    Key Record Dates
Last Update Posted: June 13, 2006
Last Verified: May 2006

Keywords provided by Orlando Regional Medical Center: