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MRSA Colonization in Peripartum Women and Their Offspring

This study has been completed.
Information provided by:
Orlando Regional Medical Center Identifier:
First received: June 9, 2006
Last updated: NA
Last verified: May 2006
History: No changes posted
We hypothesize that pregnant women are at baseline risk for carrying community-acquired MRSA, but also have frequent contact with healthcare workers which may put them at risk for hospital-acquired MRSA carriage. Our study aimed to identify the colonization rate of women in active labor and whether transmission to infants may occur.

Pregnancy Bacterial Colonization

Study Type: Observational
Study Design: Allocation: Random Sample
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: A Prospective Study of MRSA Colonization in Peripartum Women and Their Offspring

Further study details as provided by Orlando Regional Medical Center:

Estimated Enrollment: 600
Study Start Date: September 2005
Estimated Study Completion Date: May 2006
Detailed Description:
Mothers are at risk for carrying MRSA. What this risk is is not known. We have seen a dramatic increase in neonatal intensive care unit MRSA infections. Could mothers transmit MRSA to their newborns if they are asymptomatic carriers? Mothers come into close contact with health care providers, often have other children in daycare (known risk factor) and may have other exposures to MRSA. Our study was designed to sample 300 mother-infant pairs to determine whether MRSA carriage is present in asymptomatic women. The study consisted of obtaining informed consent, then performing a sterile swab of mothers' nares and vaginal area, then babies' nares and umbilicus once the baby was born.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Singleton pregnancy expected to deliver next 24 hours

Exclusion Criteria:

  • Cesarean sections
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00336427

Sponsors and Collaborators
Orlando Regional Medical Center
Principal Investigator: Margret G Reusch, MD ORMC
  More Information Identifier: NCT00336427     History of Changes
Other Study ID Numbers: ORMC-MRSA-Pregnancy
Study First Received: June 9, 2006
Last Updated: June 9, 2006

Keywords provided by Orlando Regional Medical Center:
Neonates processed this record on August 18, 2017