US-Doppler and Procoagulant Microparticles for the Diagnosis of Asymptomatic DVT in Advanced Cancer Patients With Poor Performance Status
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|ClinicalTrials.gov Identifier: NCT00336258|
Recruitment Status : Completed
First Posted : June 13, 2006
Last Update Posted : December 14, 2010
The aim of this study is to determine the prevalence of asymptomatic lower extremity DVT detected by US-Doppler and procoagulant microparticles in a selected group of cancer patients suffering from an advanced stage of the disease.
An attempt will be made to determine whether there is a correlation between this prevalence and various clinical and laboratory parameters.
|Condition or disease|
|Deep Vein Thrombosis Cancer|
The association between malignancy and venous thromboembolism(VTE) is well known. VTE is one of the most common complications seen in cancer patients Early detection of VTE can identify patients who may benefit from anticoagulant therapy and prevent morbidity and mortality.
There are recommendations for hospitalized cancer patients who are bedridden with an acute medical illness to receive prophylaxis, but in practice this is not clear cut.It has been shown, in other selected groups of patients that Ultrasound Doppler can be used in order to diagnose asymptomatic DVT (deep vein thrombosis). Hematological coagulation tests, including procoagulant microparticles will be performed for the evaluation of coagulation profile, in order to evaluate the possible correlation between the prevalence of asymptomatic DVT and these laboratory parameters.
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||US-Doppler and Procoagulant Microparticles for the Diagnosis of Asymptomatic DVT in Advanced Cancer Patients With Poor Performance Status|
|Study Start Date :||June 2006|
|Actual Primary Completion Date :||December 2010|
|Actual Study Completion Date :||December 2010|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00336258
|Rambam medical center|
|Principal Investigator:||Nira Beck-Razi||Ministry of Health, Israel|