Intragastric and Peritoneal Microdialysis in Infants With Necrotizing Enterocolitis (NEC)
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Intragastric and Intraperitoneal Microdialysis in Infants With NEC|
|Study Start Date:||October 2006|
|Study Completion Date:||May 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Neonates who are hospitalized because of suspicion of NEC are subjected to intragastric microdialysis during the observation period. The catheter is placed in the stomach via the naso-oesophageal route. If surgery is necessary a microdialysis catheter is placed in the peritoneal cavity prior to wound closure. Samples are collected every 4-hour. Samples will be analyzed continuously but the results will not be included in the clinical evaluation of the patient.
A total of 20 patients will be included in this pilot study. The results of the intragastric and peritoneal microdialysis will be compared with the clinical course, s-lactate, radiological and pathological findings in each patient.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00332592
|Surgical department A, Odense University Hospital|
|Odense, Denmark, 5000|
|Principal Investigator:||Niels Qvist, Professor||Odense University Hospital|