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Detection of Topographic Residual Acuity in Patients With Age Related Macular Degeneration

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00329277
First Posted: May 24, 2006
Last Update Posted: May 28, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University Health Network, Toronto
  Purpose

Standard perimetry provides information on topographical retinal sensitivity to light stimuli, however the said locus is not necessarily the preferred locus for fixation. Standard perimetry could also be used as a way for macular scotoma mapping, indirectly showing the fixation locus. Topographic acuity at the preferred retinal locus can be determined if correlation between loci with high sensitivity, eccentric fixation loci and potential visual acuity measurements are correlated.

PURPOSE OF THE STUDY:

Determination of visual acuity at preferred retinal locus in Low Vision patients with ARMD using eye standard automated and computerized perimetry methods.


Condition Intervention
Age-Related Macular Degeneration Procedure: perimetry

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic

Resource links provided by NLM:


Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:
  • Location of eccentric retinal locus of highest fixation accuracy

Secondary Outcome Measures:
  • Location of eccentric locus with best retinal sensitivity

Estimated Enrollment: 30
Study Start Date: April 2006
Study Completion Date: January 2008
Primary Completion Date: January 2008 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • AMD with documented pathology
  • Low Vision both eyes
  • BCVA 20/50-20/400 in best eye

Exclusion Criteria:

  • Cognitive impairment
  • Other retinal pathology
  • Previous retinal surgery
  • Significant media opacity
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00329277


Locations
Canada, Ontario
Dr S N Markowitz
Toronto, Ontario, Canada, M6H 2H1
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Samuel Markowitz, MD University Health Network, Toronto
  More Information

ClinicalTrials.gov Identifier: NCT00329277     History of Changes
Other Study ID Numbers: SNM200601
First Submitted: May 23, 2006
First Posted: May 24, 2006
Last Update Posted: May 28, 2008
Last Verified: November 2006

Keywords provided by University Health Network, Toronto:
age-related macular degeneration
preferred retinal locus
macular perimetry

Additional relevant MeSH terms:
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases