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Detection of Topographic Residual Acuity in Patients With Age Related Macular Degeneration

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ClinicalTrials.gov Identifier: NCT00329277
Recruitment Status : Completed
First Posted : May 24, 2006
Last Update Posted : May 28, 2008
Sponsor:
Information provided by:
University Health Network, Toronto

Brief Summary:

Standard perimetry provides information on topographical retinal sensitivity to light stimuli, however the said locus is not necessarily the preferred locus for fixation. Standard perimetry could also be used as a way for macular scotoma mapping, indirectly showing the fixation locus. Topographic acuity at the preferred retinal locus can be determined if correlation between loci with high sensitivity, eccentric fixation loci and potential visual acuity measurements are correlated.

PURPOSE OF THE STUDY:

Determination of visual acuity at preferred retinal locus in Low Vision patients with ARMD using eye standard automated and computerized perimetry methods.


Condition or disease Intervention/treatment Phase
Age-Related Macular Degeneration Procedure: perimetry Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Study Start Date : April 2006
Actual Primary Completion Date : January 2008
Actual Study Completion Date : January 2008

Resource links provided by the National Library of Medicine

U.S. FDA Resources




Primary Outcome Measures :
  1. Location of eccentric retinal locus of highest fixation accuracy

Secondary Outcome Measures :
  1. Location of eccentric locus with best retinal sensitivity


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • AMD with documented pathology
  • Low Vision both eyes
  • BCVA 20/50-20/400 in best eye

Exclusion Criteria:

  • Cognitive impairment
  • Other retinal pathology
  • Previous retinal surgery
  • Significant media opacity

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00329277


Locations
Canada, Ontario
Dr S N Markowitz
Toronto, Ontario, Canada, M6H 2H1
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Samuel Markowitz, MD University Health Network, Toronto

ClinicalTrials.gov Identifier: NCT00329277     History of Changes
Other Study ID Numbers: SNM200601
First Posted: May 24, 2006    Key Record Dates
Last Update Posted: May 28, 2008
Last Verified: November 2006

Keywords provided by University Health Network, Toronto:
age-related macular degeneration
preferred retinal locus
macular perimetry

Additional relevant MeSH terms:
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases