Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer
A study to examine the potential associations between common single nucleotide polymorphisms and pre-cancerous conditions in breast tissue specimens from postmenopausal women.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Correlation of SNP Patterns With Fine Needle Aspiration Cytomorphology in High Risk Postmenopausal Women|
- Correlation of SNP patterns with cytlomorphology of breast fine needle aspirates. [ Time Frame: ongoing ] [ Designated as safety issue: No ]develoment of algorithm for prediction of risk of developing breast cancer.
Biospecimen Retention: Samples With DNA
Fine needle aspirate
|Study Start Date:||May 2005|
|Estimated Study Completion Date:||May 2016|
|Estimated Primary Completion Date:||May 2016 (Final data collection date for primary outcome measure)|
Post-menopausal women who are at increased risk for development of breast cancer on the basis of family or personal history.
Procedure: Fine needle aspiration
Fine needle aspiration
Other Name: Fine needle aspiration
A study to examine the correlation between single nucleotide polymorphisms (SNPs) affecting steroid and carcinogen metabolism and benign breast tissue cytomorphology collected via random periareolar fine needle aspiration in postmenopausal women at increased risk for breast cancer and taking hormone replacement therapy.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00329017
|United States, Kansas|
|University of Kansas Medical Center|
|Kansas City, Kansas, United States, 66160|
|Principal Investigator:||Carol J Fabian, MD||University of Kansas|