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Cardiac SPECT With Rotating Slant Hole Collimator

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2007 by Johns Hopkins University.
Recruitment status was:  Recruiting
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Information provided by:
Johns Hopkins University Identifier:
First received: May 18, 2006
Last updated: January 3, 2007
Last verified: January 2007
The goal is to conduct a clinical pilot study to evaluate the use of a rotating multi-segment slant-hole collimator in the detection of myocardial defects.

Coronary Artery Diseases
Chest Pain

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective

Further study details as provided by Johns Hopkins University:

Estimated Enrollment: 60
Study Start Date: October 2006
Detailed Description:

Myocardial perfusion SPECT is recognized as an effective clinical diagnostic imaging technique in the assessment of myocardial perfusion and coronary artery diseases. It is the most important clinical application of SPECT imaging techniques.

The goal is to conduct a clinical pilot study to evaluate the use of RMSSH SPECT in the detection of myocardial defects especially in very sick patients in the nuclear medicine clinics, emergence room, and intensive care units. Comparison of the clinical utilities of the cardiac RMSSH SPECT technique with conventional cardiac planar and SPECT with parallel-hole collimation will also allow us to evaluate the potential application of the technique to a wider patient population.

The objective of this study is to test the hypothesis that quantitative 99mTc myocardial perfusion RMSSH SPECT provides similar diagnostic accuracy in patients with cardiac diseases as conventional SPECT imaging techniques.


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Males and Females 18-80 who are scheduled for a clinical Cardiac Stress Test

Exclusion Criteria:

  • Pregnant Women and Children
  Contacts and Locations
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Please refer to this study by its identifier: NCT00328315

Contact: Linda Wilkins, RT, CCRP 410-955-8216

United States, Maryland
Johns Hopkins Outpatient Center Recruiting
Baltimore, Maryland, United States, 21287
Contact: Linda Wilkins, RT, CCRP    410-955-8216      
Sponsors and Collaborators
Johns Hopkins University
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Principal Investigator: Benjamin Tsui, Ph.D. Johns Hopkins University
  More Information Identifier: NCT00328315     History of Changes
Other Study ID Numbers: R01 EB 0019-83
Study First Received: May 18, 2006
Last Updated: January 3, 2007

Keywords provided by Johns Hopkins University:
Myocardial Perfusion SPECT

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Chest Pain
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on May 25, 2017