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Cardiac SPECT With Rotating Slant Hole Collimator

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ClinicalTrials.gov Identifier: NCT00328315
Recruitment Status : Unknown
Verified January 2007 by Johns Hopkins University.
Recruitment status was:  Recruiting
First Posted : May 19, 2006
Last Update Posted : January 4, 2007
Information provided by:

Study Description
Brief Summary:
The goal is to conduct a clinical pilot study to evaluate the use of a rotating multi-segment slant-hole collimator in the detection of myocardial defects.

Condition or disease
Coronary Artery Diseases Chest Pain

Detailed Description:

Myocardial perfusion SPECT is recognized as an effective clinical diagnostic imaging technique in the assessment of myocardial perfusion and coronary artery diseases. It is the most important clinical application of SPECT imaging techniques.

The goal is to conduct a clinical pilot study to evaluate the use of RMSSH SPECT in the detection of myocardial defects especially in very sick patients in the nuclear medicine clinics, emergence room, and intensive care units. Comparison of the clinical utilities of the cardiac RMSSH SPECT technique with conventional cardiac planar and SPECT with parallel-hole collimation will also allow us to evaluate the potential application of the technique to a wider patient population.

The objective of this study is to test the hypothesis that quantitative 99mTc myocardial perfusion RMSSH SPECT provides similar diagnostic accuracy in patients with cardiac diseases as conventional SPECT imaging techniques.

Study Design

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Study Start Date : October 2006
Groups and Cohorts

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Males and Females 18-80 who are scheduled for a clinical Cardiac Stress Test

Exclusion Criteria:

  • Pregnant Women and Children
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00328315

Contact: Linda Wilkins, RT, CCRP 410-955-8216 lwilkins@jhmi.edu

United States, Maryland
Johns Hopkins Outpatient Center Recruiting
Baltimore, Maryland, United States, 21287
Contact: Linda Wilkins, RT, CCRP    410-955-8216      
Sponsors and Collaborators
Johns Hopkins University
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Principal Investigator: Benjamin Tsui, Ph.D. Johns Hopkins University
More Information

ClinicalTrials.gov Identifier: NCT00328315     History of Changes
Other Study ID Numbers: R01 EB 0019-83
First Posted: May 19, 2006    Key Record Dates
Last Update Posted: January 4, 2007
Last Verified: January 2007

Keywords provided by Johns Hopkins University:
Myocardial Perfusion SPECT

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Chest Pain
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms