This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Clinical Outcome of Neonates With GBS Positive Culture-12 Year Retrospective Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2006 by Sheba Medical Center.
Recruitment status was:  Not yet recruiting
Information provided by:
Sheba Medical Center Identifier:
First received: May 14, 2006
Last updated: May 15, 2006
Last verified: May 2006

Streptococci group B (GBS) is a the major reason for morbidity and mortality in neonates. It can present as pneumonia ,meningitis or sepsis.The mortality today is 5-20% and even more in preterm babies.

During the past two decade, the introduction of protocols for prophylactic antibiotics for women with a high risk for GBS infection, have led to a decline of 65% in GBS cases(0.32 for 1000 live birth compared to 1.8 cases in 1000).The purpose of the study is to check the morbidity and mortality at Sheba medical center in the last 12 years in children with positive blood culture for GBS. We assume that in our hospital the morbidity and mortality is less then expected. If proven right, we would then check the reasons for that outcome considering the type and length of treatment and the different virulence of the streptococcus.

Infants With Positive GBS Bacteremia

Study Type: Observational
Official Title: Clinical Outcome of Neonate With GBS Positive Culture-12 Year Retrospective Study

Further study details as provided by Sheba Medical Center:

Estimated Enrollment: 74
Study Start Date: June 2006
Detailed Description:
This is a retrospective case control study. We will review from archive the charts of all the neonates with positive blood culture for GBS, reviewing the course and severity of their illness.

Ages Eligible for Study:   up to 2 Weeks   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • GBS positive blood culture neonate and preterm babies

Exclusion Criteria:

  • Congenital malformations
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00326313

Sponsors and Collaborators
Sheba Medical Center
Principal Investigator: Tzipora Strauss, MD Sheba Medical Center
  More Information Identifier: NCT00326313     History of Changes
Other Study ID Numbers: SHEBA-06-4132-TS-CTIL
Study First Received: May 14, 2006
Last Updated: May 15, 2006

Keywords provided by Sheba Medical Center:
Group B streptococci

Additional relevant MeSH terms:
Bacterial Infections
Systemic Inflammatory Response Syndrome
Pathologic Processes processed this record on August 18, 2017