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The Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic Cardiomyopathy

This study has been terminated.
(no financial resources were available to complete the study)
Information provided by (Responsible Party):
Offer Amir, Carmel Medical Center Identifier:
First received: May 5, 2006
Last updated: January 24, 2012
Last verified: January 2007
In many of the patients with cardiomyopathy, the etiology is not clear . In about 30% there is a family history of cardiomyopathy .Our aim is to study the genetics basis for these patients with cardiomyopathy with no clear etiology and who have a first degree family relative with cardiomyopathy as well.


Study Type: Observational
Study Design: Observational Model: Family-Based
Time Perspective: Prospective
Official Title: Open Labeled of the Study the Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic

Resource links provided by NLM:

Further study details as provided by Carmel Medical Center:

Biospecimen Retention:   Samples With DNA
Blood samples

Enrollment: 41
Study Start Date: May 2007
Study Completion Date: February 2009
Primary Completion Date: February 2009 (Final data collection date for primary outcome measure)
Detailed Description:
A total of 950 blood samples will be collected from patients with idiopathic cardiomyopathy and their relatives and will be analysed for genetics analysis.

Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
History of cardiomyopathy

Inclusion Criteria:

  • history of cardiomyopathy
  • etiology not known
  • family history of cardiomyopathy
  • ability to understand and sign the informed consent

Exclusion Criteria:

  • refusal to participate
  • pregnancy
  • current participation in another active treatment study
  Contacts and Locations
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Please refer to this study by its identifier: NCT00322582

Carmel Medical Center
Haifa, Israel, 34362
Sponsors and Collaborators
Carmel Medical Center
Study Director: Offer Amir, MD Lady Davis Carmel Hospital
  More Information

Responsible Party: Offer Amir, Offer Amir, MD, Carmel Medical Center, Carmel Medical Center Identifier: NCT00322582     History of Changes
Other Study ID Numbers: GEN/ICM
Study First Received: May 5, 2006
Last Updated: January 24, 2012

Keywords provided by Carmel Medical Center:
familial cardiomyopathy
genetics analysis

Additional relevant MeSH terms:
Heart Diseases
Cardiovascular Diseases processed this record on May 22, 2017