LV Thrombus Pilot Study for Comparing Enoxaparin Vs. Warfarin
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00321009|
Recruitment Status : Completed
First Posted : May 3, 2006
Last Update Posted : May 3, 2006
|Condition or disease||Intervention/treatment||Phase|
|Coronary Artery Disease Acute Myocardial Infarction||Drug: Enoxaparin||Not Applicable|
Patients with anterior Q-wave MIs and ejection fractions<=40% will be enrolled within the first 4 days of infarction. Patients will be randomized to receive either enoxaparin 1mg/kg (maximum 100mg) subcutaneously every 12 hours for one month or heparin followed by oral warfarin for 3 months.
Clinical and safety evaluations, 2-D echocardiograms at baseline and at 3.5 months and cost analysis will be performed.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||60 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Prospective Randomized Trial Comparing Enoxaparin to Warfarin for the Prevention of LV Thrombus Formation After Anterior Wall Myocardial Infarction: A 60 Patient Pilot Study|
|Study Start Date :||March 2000|
|Study Completion Date :||April 2004|
- What is the incidence of LV mural thrombus with administration of enoxaparin vs.
- warfarin at 3.5 months in patients presenting with anterior wall myocardial
- What are the associated costs and length of hospital stay after randomized to
- enoxaparin vs. warfarin?
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00321009
|United States, Colorado|
|University of Colorado Health Sciences Center|
|Denver, Colorado, United States, 80262|
|United States, Michigan|
|William Beaumont Hospital|
|Royal Oak, Michigan, United States, 48073|
|United States, New York|
|St Joseph's Health Center Dept. of Cardiology|
|Syracuse, New York, United States, 13203|
|United States, North Carolina|
|LaBauer Cardiovascular Research Foundation|
|Greensboro, North Carolina, United States, 27403|
|United States, Pennsylvania|
|Doylestown, Pennsylvania, United States, 18901|
|United States, Virginia|
|Cardiovascular Associates Ltd.|
|Virginia Beach, Virginia, United States, 23454|
|Principal Investigator:||Cindy L Grines, MD||William Beaumont Hospitals|