EEG Studies of Sensory Processing in Autistic Children
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ClinicalTrials.gov Identifier: NCT00319722
Verified May 2010 by Massachusetts General Hospital. Recruitment status was: Recruiting
This study uses EEG to study brain waves at rest and in response to specific auditory and visual sensory stimuli in autistic children. We hypothesize that, compared to same age peers, autistics will show abnormalities in their electrophysiologic processing of sounds (tones and phonemes)and visual stimuli (flashes of light)and that these abnormalities will be able to separate autistics not only from typical children but also into clinical subgroups with specific biological/electrophysiological characteristics. We hope to find biological measures which will prove diagnostic of autism in very young children and which can be used in the measurement of treatment outcome in future intervention trials.
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Ages Eligible for Study:
3 Months to 8 Years (Child)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
autistic children meeting criteria for autism based on ADOS and ADI and clinical DSM IV or their siblings between the ages of 3 months to 13 years.
autistic children or their younger siblings between the ages of 3 months to 8 year
Controls: typically developing children 3mo to 8 years without known language or social disorder and not related to child with autism
Exclusion Criteria: progressive encephalopathy, treatment with multiple antiepileptic drugs, known genetic diagnosis.