Efficacy of rTMS in the Treatment of Patients With Migraine

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.

Verified June 2010 by Taipei Veterans General Hospital, Taiwan.
Recruitment status was: Recruiting

Sponsor:

Collaborator:

National Science Council, Taiwan

Information provided by:

Taipei Veterans General Hospital, Taiwan

ClinicalTrials.gov Identifier:

NCT00316979

First received: April 20, 2006

Last updated: June 6, 2010

Last verified: June 2010

History of Changes

Purpose

Migraine is a condition thought to be related to cortical hyperexcitability. Repetitive transcranial magnetic stimulation (rTMS) can modulate the cortical excitability by means of long-term potentiation or long-term depression. This study will will test the safety and efficacy of rTMS in the treatment of patients with Migraine.

Condition	Intervention
Migraine	Device: Repetitive Transcranial Magnetic Stimulation (rTMS)


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double-Blind Primary Purpose: Treatment
Official Title:	Therapeutic Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Migraine Using Somatosensory Evoked High-Frequency Oscillations as a Parameter: A 3-year Study.

Resource links provided by NLM:

MedlinePlus related topics: Migraine

U.S. FDA Resources

Further study details as provided by Taipei Veterans General Hospital, Taiwan:

Primary Outcome Measures:

Reduction in days of migraine attack per month

Secondary Outcome Measures:

The reduction in dosage of acute abortive medication
The reduction of headache index


Estimated Enrollment:	80
Study Start Date:	April 2006

Eligibility


Ages Eligible for Study:	18 Years to 65 Years (Adult)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Age of 18-65 years
Diagnosed as migraine (with or without aura)
More than 4 attacks per month for at least 3 months prior to study
No preventive medication used
Must be able to sign permit

Exclusion Criteria:

History of seizure or family history of seizures
Women in pregnancy or breast-feeding
Patient with medication overuse
Patient with other medical, psychologic, or surgical illness
Patient under preventive medications
Prior rTMS examination one month within

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00316979

Contacts


Contact: Shuu-Jiun Wang, MD	+886-2-28712121 ext 2425	sjwang@vghtpe.gov.tw
Contact: Kuan-Lin Lai, MD	+886-2-28712121 ext 3185	kllai@vghtpe.gov.tw

Locations


Taiwan
Headache Center, Teipei Veterans General Hospital	Recruiting
Taipei, Taiwan, 112
Contact: Shuu-Jiun Wang, MD +886-2-28712121 ext 2425 sjwang@vghtpe.gov.tw
Contact: Jong-Ling Fuh, MD +886-2-28712121 ext 3256 jlfuh@vghtpe.gov.tw
Principal Investigator: Shuu-Jiun Wang, MD

Sponsors and Collaborators

Taipei Veterans General Hospital, Taiwan

National Science Council, Taiwan

Investigators


Principal Investigator:	Shuu-Jiun Wang, MD	Headache Center, Taipei Veterans General Hospital

More Information

Publications:

Brighina F, Piazza A, Vitello G, Aloisio A, Palermo A, Daniele O, Fierro B. rTMS of the prefrontal cortex in the treatment of chronic migraine: a pilot study. J Neurol Sci. 2004 Dec 15;227(1):67-71.

Lorenz J, Minoshima S, Casey KL. Keeping pain out of mind: the role of the dorsolateral prefrontal cortex in pain modulation. Brain. 2003 May;126(Pt 5):1079-91.


ClinicalTrials.gov Identifier:	NCT00316979 History of Changes
Other Study ID Numbers:	rTMS_Migraine_VGHTPE
Study First Received:	April 20, 2006
Last Updated:	June 6, 2010

Keywords provided by Taipei Veterans General Hospital, Taiwan:


migraine transcranial magnetic stimulation repetitive transcranial magnetic stimulation rTMS

Additional relevant MeSH terms:


Migraine Disorders Headache Disorders, Primary Headache Disorders	Brain Diseases Central Nervous System Diseases Nervous System Diseases

ClinicalTrials.gov processed this record on July 18, 2017

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