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Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2006 by Far Eastern Memorial Hospital.
Recruitment status was:  Not yet recruiting
National Taiwan University
Information provided by:
Far Eastern Memorial Hospital Identifier:
First received: April 12, 2006
Last updated: April 14, 2006
Last verified: April 2006
The purpose of this study is to compare movement variations before and after the loaded training, with kinematics, kinetics, and electromyography, in children with spastic diplegia and to further discuss mechanisms of the loaded training.

Condition Intervention
Cerebral Palsy Device: loaded sit-to-stand training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Educational/Counseling/Training
Official Title: Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia Before and After Loaded Sit-to-Stand Training

Resource links provided by NLM:

Further study details as provided by Far Eastern Memorial Hospital:

Primary Outcome Measures:
  • kinematic measures of lower extremity and the whole body
  • kinetic measures of lower extremity and the whole body
  • electromyographic measures of lower extremity and the whole body

Estimated Enrollment: 20
Study Start Date: April 2006
Estimated Study Completion Date: September 2007
Detailed Description:

Subjects: This study will recruit twenty children who are aged between 5 and 12 years, with spastic diplegia, and without having major surgeries or botulinum toxin injection on lower extremities during the past 6 months prior to participate in this study.

Methods: The Vicon 250 motion analysis system, 3 AMTI force platforms and the EMG recording system will be used to collect data of sit-to-stand (STS) movements. Baseline, pre- and post-training evaluations will be carried out. The duration of the baseline and pre-training evaluations is 2 months. The training period will take about 6 weeks. Each evaluation will take two separate days to accomplish. On the first day, the STS1RM of individual children was determined. On the second day, kinematic and kinetic data of STS movements in natural and loaded (applying load of 50% STS1RM during STS movements) conditions were collected. Data of smoothness, maximal extension moment and around hip and knee joints, onset time of lower extremity muscles will then be calculated. Results of each evaluation will be used for further comparison.


Ages Eligible for Study:   5 Years to 12 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosed as spastic diplegia
  • Aged between 5 and 12 years
  • Able to perform the STS movements without assistance
  • Able to cooperate and understand commands given

Exclusion Criteria:

  • Severe musculoskeletal deformity or pain on lower extremities
  • Botulism injection in the past 3 months or major operations in the preceding 6 months on lower extremities
  • Uncontrolled epilepsy
  • Major sensory deficits, such as blindness or deafness
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00314301

Contact: Yuh-Ting Lin, MSc 866-2-8966-7000 ext 1411
Contact: Jao-Shwann Liang, MD 866-2-8966-7000 ext 1411

National Taiwan University Hospital Not yet recruiting
Taipei, Taiwan, 100
Contact: Hua-Fang Liao, MPH    886-2-3322\8136   
Principal Investigator: Yuh-Ting Lin, MSc         
Sponsors and Collaborators
Far Eastern Memorial Hospital
National Taiwan University
Principal Investigator: Yuh-Ting Lin, MSc Research Ethics Review Committee of the Far Eastern Memorial Hospital
  More Information Identifier: NCT00314301     History of Changes
Other Study ID Numbers: 94023
Study First Received: April 12, 2006
Last Updated: April 14, 2006

Keywords provided by Far Eastern Memorial Hospital:
cerebral palsy

Additional relevant MeSH terms:
Cerebral Palsy
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases processed this record on August 17, 2017