Thalamic Deep Brain Stimulation for Tourette Syndrome
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
age 18 or older
Diagnosis of Tourette Syndrome by DSM-IV
Tic frequency at least one per minute at screening
prior failure of at least two dopamine receptor or presynaptic blockers
negative impact on quality of life
significant structural brain lesion (on imaging studies)
severe head trauma preceding onset of tics
use of dopamine receptor blockers prior to recognition of tics