Impact of Patient-Prosthesis-Mismatch on Coronary Flow Reserve

This study has been completed.
Information provided by:
Johann Wolfgang Goethe University Hospitals Identifier:
First received: March 31, 2006
Last updated: April 4, 2006
Last verified: March 2003
Complete normalization of CFR following AVR for aortic stenosis was observed only for stentless valves. Besides the superior hemodynamic performance this might explain the excellent long term results of this valve design.

Coronary Artery Disease

Study Type: Observational
Study Design: Allocation: Random Sample
Observational Model: Natural History
Time Perspective: Longitudinal
Official Title: Impact of Patient-Prosthesis-Mismatch and Aortic Valve Design on Coronary Flow Reserve Following Aortic Valve Replacement

Resource links provided by NLM:

Further study details as provided by Johann Wolfgang Goethe University Hospitals:

Estimated Enrollment: 48
Study Start Date: March 2005
Estimated Study Completion Date: January 2006

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Aortic valve stenosis

Exclusion Criteria:

Coronary artery disease

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00310947

JW Goethe University Ffm
Frankfurt am Main, Hessen, Germany, 60590
Sponsors and Collaborators
Johann Wolfgang Goethe University Hospitals
Principal Investigator: Peter Kleine, MD,PhD JW Goethe University Ffm
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00310947     History of Changes
Other Study ID Numbers: Coronary flow reserve 
Study First Received: March 31, 2006
Last Updated: April 4, 2006
Health Authority: Germany: Ethics Commission

Keywords provided by Johann Wolfgang Goethe University Hospitals:
Coronary artery disease
Coronary flow reserve
Heart failure
prospective randomised

Additional relevant MeSH terms:
Coronary Artery Disease
Coronary Disease
Myocardial Ischemia
Arterial Occlusive Diseases
Cardiovascular Diseases
Heart Diseases
Vascular Diseases processed this record on May 26, 2016