Acupuncture for Elevated Intraocular Pressure

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00307918
Recruitment Status : Terminated (lack of patients)
First Posted : March 28, 2006
Last Update Posted : October 2, 2007
Information provided by:
Shaare Zedek Medical Center

Brief Summary:
Glaucoma is the leading cause of irreversible blindness in the world, resulting from progressive axonal destruction of the optic nerve. Primary open-angle glaucoma is the most common form, and it is usually painless with insidious onset. Conventional treatment is focused on lowering intraocular pressure (IOP), the one risk factor that can be modified, which has been demonstrated to protect against further damage to the optic-nerve head. Acupuncture is an ancient treatment which has been found to be beneficial for many ailments, and may reduce IOP. We propose a pilot study to evaluate whether acupuncture is an effective and safe modality for reducing elevated IOP in patients with open angle glaucoma and primary ocular hypertension. Patients with elevated IOP on tonometric measurement (20mmHg < IOP < 30mmHg) will be treated twice-weekly with a standardized (as opposed to individualized) acupuncture treatment. Treatment will last for four-weeks (for a total of 8 treatments), and patients will be evaluated for IOP diurnal curves at 2 weeks (4 treatment), 4 weeks (end of treatment ) and then 4 weeks following the last treatment.

Condition or disease Intervention/treatment Phase
Elevated Intraocular Pressure Device: acupuncture Phase 3

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 10 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Acupuncture Treatment for Elevated Intraocular Pressure: A Pilot Study
Study Start Date : May 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Acupuncture

Primary Outcome Measures :
  1. Intraocular pressure curves.

Secondary Outcome Measures :
  1. safety of acupuncture treatment

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

patients of either gender; age 21 years and older; intraocular pressure equal/greater than 20mmHg, equal/less than 30mmHg; ability to comply with study protocol

Exclusion Criteria:

patients with secondary or closed-angle glaucoma; patients with a history of laser or other surgical treatment of glaucoma; patients displaying symptoms of depression, anxiety or psychosis

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00307918

Dept. of Ophthalmology, Shaare Zedek Medical Center
Jerusalem, Israel, 91031
Sponsors and Collaborators
Shaare Zedek Medical Center
Principal Investigator: Menachem Oberbaum, M.D. Shaare Zedek Medical Center, Jerusalem, Israel Identifier: NCT00307918     History of Changes
Other Study ID Numbers: ACP GL 01 06 CTIL
First Posted: March 28, 2006    Key Record Dates
Last Update Posted: October 2, 2007
Last Verified: September 2007

Keywords provided by Shaare Zedek Medical Center:
acupuncture, intraocular pressure, glaucoma

Additional relevant MeSH terms:
Ocular Hypertension
Eye Diseases