Emphysema Research Registry

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2015 by University of Pittsburgh
Sponsor:
Information provided by (Responsible Party):
Frank C Sciurba, University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT00307281
First received: March 24, 2006
Last updated: December 1, 2015
Last verified: December 2015
  Purpose
The Comprehensive Lung Center (CLC) at the University of Pittsburgh Medical Center (UPMC Health System) provides patients with any type of breathing or lung disorder a full range of diagnostic and therapeutic services. The Emphysema Research Center (ERC) is a specialty clinic, within this center, that attempts to advance the understanding of emphysema and to evaluate new therapies for patients with emphysema. The Emphysema Research Registry will enable pulmonary research physicians to: 1) gather information and create a research registry of people who have been diagnosed with emphysema; 2) utilize this research registry with the purpose of conducting research that attempts to advance the understanding of emphysema and to evaluate new therapies; and, 3) use the research registry to identify potential candidates for future research programs. These aims will be achieved by the collection of DNA (genetic material)for analysis and storage in addition to pulmonary function tests and other medical information.

Condition Intervention
Emphysema
Chronic Obstructive Pulmonary Disease
Chronic Bronchitis
Other: Phlebotomy, Pulmonary Function Tests

Study Type: Observational [Patient Registry]
Study Design: Observational Model: Cohort
Target Follow-Up Duration: 2 Years
Official Title: Emphysema Research Registry; Screening Study and Genetic Testing

Resource links provided by NLM:


Further study details as provided by University of Pittsburgh:

Primary Outcome Measures:
  • This research registry will allow us to tap into this resource and address important, unanswered questions about the disease process and new therapies. [ Time Frame: Indefinite ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • To continue communications with past, present, and future research participants. [ Time Frame: Indefinite ] [ Designated as safety issue: No ]

Estimated Enrollment: 3000
Study Start Date: August 2000
Estimated Study Completion Date: July 2030
Estimated Primary Completion Date: July 2030 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Registry
10 pack year tobacco smoking history required, current or former smokers accepted.
Other: Phlebotomy, Pulmonary Function Tests

  Show Detailed Description

  Eligibility

Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Current and former smokers with a 10 pack year tobacco history.
Criteria

Inclusion Criteria:

  • Patients would be required to have COPD based on at least one of the following: clinical history, pulmonary function results, or radiographic results.

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00307281

Contacts
Contact: Paula Consolaro, CCRC 412-692-4800 consolaropj@upmc.edu
Contact: Mary Bryner, RRT

Locations
United States, Pennsylvania
University of Pittsburgh Emphysema Research Center Recruiting
Pittsburgh, Pennsylvania, United States, 15213
Contact    412-692-4800    ecrc@upmc.edu   
Contact    1-866-948-COPD(2673)    ecrc@upmc.edu   
Principal Investigator: Frank C. Sciurba, MD         
Sub-Investigator: Jessica M. Bon, MD         
Sub-Investigator: John Tedrow, MD         
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: Frank C. Sciurba, MD University of Pittsburgh
  More Information

Responsible Party: Frank C Sciurba, Director, Emphysema/COPD Research Center, University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00307281     History of Changes
Other Study ID Numbers: UofP ERC Registry  ERC Registry 
Study First Received: March 24, 2006
Last Updated: December 1, 2015
Health Authority: United States: Institutional Review Board
Individual Participant Data  
Plan to Share IPD: Undecided

Additional relevant MeSH terms:
Bronchitis, Chronic
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Emphysema
Pulmonary Emphysema
Bronchitis
Respiratory Tract Diseases
Pathologic Processes
Bronchial Diseases
Respiratory Tract Infections

ClinicalTrials.gov processed this record on August 25, 2016