Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00306124|
Recruitment Status : Unknown
Verified October 2007 by University Hospital Muenster.
Recruitment status was: Recruiting
First Posted : March 22, 2006
Last Update Posted : October 25, 2007
This study aims to determine whether levodopa is effective in boosting learning and memory in healthy subjects and patients with dementia or Mild Cognitive Impairment.
We also examine in healthy subjects using functional magnetic resonance imaging which brain regions mediate improved learning after levodopa administration.
|Condition or disease||Intervention/treatment||Phase|
|Alzheimer's Disease Mild Cognitive Impairment Healthy||Drug: Levodopa||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||120 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Dopaminergic Enhancement of Learning and Memory (LL_001, Project on Dementia/MCI)|
|Study Start Date :||January 2006|
|Estimated Study Completion Date :||March 2008|
- Cognitive performance assessed by neuropsychological tests and learning paradigms under placebo and levodopa in healthy subjects and patients with dementia or Mild Cognitive Impairment.
- Brain activity pattern during learning under levodopa as compared to placebo in healthy subjects.
- Long-term stability of learning performance after 1 month in healthy subjects.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00306124
|Contact: Bernward Winter, MSc||+49-251-83 ext email@example.com|
|University of Muenster, Department of Neurology||Recruiting|
|Muenster, North-Rhine Westphalia, Germany, 48129|
|Principal Investigator:||Stefan Knecht, MD||Neurology, University of Muenster, Germany|
|Principal Investigator:||Caterina Breitenstein, PhD||Neurology, University of Muenster, Germany|
|Study Director:||Julia Reinholz, PhD||Neurology, University of Muenster, Germany|