Autologous Bone Marrow Cell Treatment in Peripheral Atherosclerosis
Recruitment status was Recruiting
Implantation of bone marrow cells, including endothelial progenitor cells, into ischemic limbs has been shown to improve collateral vessel formation. In the present study the safety and feasibility of autologous blood mononuclear cells implantation will be investigated in patients with severe peripheral atherosclerosis.Twenty cases will be enrolled. Improvement in the ankle-brachial pressure index (ABI:>0.1), ischemic ulcers and angiography as well as laser doppler flow will be evaluated until six months.
Peripheral Vascular Diseases
Genetic: Autologous bone marrow cells
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Primary Purpose: Treatment
|Official Title:||Autologous Bone Marrow Cell Treatment in Patients With Peripheral Atherosclerosis|
- Clinical and instrumental indexes of functional impairment of peripheral atherosclerosis.
- Angiographic and laser doppler measurements after six months from treatment.
|Study Start Date:||April 2005|
|Estimated Study Completion Date:||April 2006|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00306085
|Contact: Heidi Eisele||+39 firstname.lastname@example.org|
|University of Naples||Recruiting|
|Naples, Italy, 80134|
|Contact: Maria Carmela Corbisiero +39081/5665681 email@example.com|
|Study Director:||Vincenzo Sica||University of Naples|