Study of Admission Versus Discharge After Transient Ischemic Attack (TIA)

This study has been withdrawn prior to enrollment.
Information provided by:
University of California, San Diego Identifier:
First received: March 16, 2006
Last updated: February 3, 2015
Last verified: March 2007
Evaluate for difference in outcome between hospital admission versus discharge after recent TIA, and evaluate feasibility of a larger study.

Condition Intervention Phase
Transient Ischemic Attack (TIA)
Behavioral: Hospital admission
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Pilot Study of Admission Versus Discharge After Transient Ischemic Attack (TIA)

Resource links provided by NLM:

Further study details as provided by University of California, San Diego:

Primary Outcome Measures:
  • modified Rankin Scale at one year. [ Time Frame: 1 year ]

Secondary Outcome Measures:
  • Stroke and TIA incidence at one year [ Time Frame: 1 year ]

Enrollment: 0
Study Start Date: March 2006
Study Completion Date: March 2007
Arms Assigned Interventions
Experimental: Admission
Behavioral: Hospital admission
No Intervention: Discharge

Detailed Description:
20 patients will be randomized within 24 hours of a TIA to be admitted to the hospital or discharged to home, and the investigator will compare outcomes, cost, and evaluate the feasibility of a larger study.

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age 18 and older.
  • Clinical diagnosis of TIA within 24 hours of consent.

Exclusion Criteria:

  • Crescendo TIAs, defined as multiple within 24 hours of presentation.
  • Posterior circulation TIAs diagnosed clinically by a member of the Stroke Team.
  • High grade carotid stenosis.
  • Any compelling medical reason they should or should not be admitted or discharged (for example decompensated congestive heart failure, unstable angina, new EKG changes, pneumonia, sepsis). Patients will only be enrolled if the only consideration for admission is the TIA, and they otherwise meet appropriate standard of care criteria for discharge to home.
  • Patients will be excluded if no one can be with them for the next 12 hours to ensure a rapid call to 911 should problems arise, specifically stroke.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00304798

United States, California
San Diego, California, United States, 92103
Sponsors and Collaborators
University of California, San Diego
Principal Investigator: Matt B Jensen, MD UCSD Stroke Center
  More Information Identifier: NCT00304798     History of Changes
Other Study ID Numbers: UCSD IRB #051272 
Study First Received: March 16, 2006
Last Updated: February 3, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, San Diego:
Transient Ischemic Attack (TIA).
Hospital admission.

Additional relevant MeSH terms:
Ischemic Attack, Transient
Brain Diseases
Brain Ischemia
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Nervous System Diseases
Pathologic Processes
Vascular Diseases processed this record on May 24, 2016