In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome
|ClinicalTrials.gov Identifier: NCT00302874|
Recruitment Status : Completed
First Posted : March 15, 2006
Last Update Posted : March 26, 2007
To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.
The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.
- All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.
- At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.
- During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.
- During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.
- During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.
- Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.
|Condition or disease||Intervention/treatment|
|Diabetes Hyperglycemia||Behavioral: Implementation of a protocol for treatment of hyperglycemia|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||400 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome|
|Study Start Date :||February 2003|
|Estimated Study Completion Date :||October 2004|
- Mean blood glucose during hospitalization
- Hypoglycemic events
- Length of in-hospital stay
- Complications (myocardial infarction, stroke)
- Disposition at discharge (home, nursing home)
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00302874
|Hadassah Medical Organization|
|Jerusalem, Israel, 91120|
|Principal Investigator:||Gil Leibowitz, MD||Hadassah Medical Organization|