Use of Bisphosphonates in the Treatment of Osteopathy After Liver Transplantation
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ClinicalTrials.gov Identifier: NCT00302484
Verified January 2006 by Medical University of Vienna. Recruitment status was: Active, not recruiting
Patients with a terminal chronic liver disease have a disordered bone metabolism resulting in a higher risk of falling ill with osteoporosis. Although liver transplantation restores liver function, immunosuppressive therapy (especially corticosteroids) after transplantation increases again the risk of osteoporosis and bone fragility. Zoledronate, a bisphosphonate, slows down the destruction of bone. The purpose of this study is to determine whether bisphosphonates are effective in the prevention of osteoporosis following immunosuppressive therapy after liver transplantation.
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