Short or Long Schemes of Antibiotic Prophylaxis for Prostate Biopsy
Men Who Must Undergo a Prostate Biopsy Related to Prostate Cancer Suspicion.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Comparison Between Short and Long Schemes of Antibiotic Prophylaxis for Transrectal Prostate Biopsy. A Multicentre Prospective Randomised Study|
- Bacteriuria five days after prostate biopsy
- - Clinically diagnosed infectious complications
- - Other complications related to the procedure
|Study Start Date:||February 2006|
|Study Completion Date:||April 2008|
|Primary Completion Date:||December 2007 (Final data collection date for primary outcome measure)|
Prophylactic antibiotic is used to minimize the infective complications risk following transrectal biopsy of the prostate.
The majority of works points to the need of antibiotic prophylaxis previously to transrectal prostate biopsy. However, there is a lot of controversy and diversity of therapeutic schemes in the literature concerning the ideal drug to be used and the time employed for infectious prophylaxis.
The objective of this randomised study was to assess 2 different schemes of antimicrobial prophylaxis, aiming to determine the difference in infective complications with a single dose of ciprofloxacin 2 hours before the procedure vs. ciprofloxacin for 3 days
Please refer to this study by its ClinicalTrials.gov identifier: NCT00294749
|Poitiers Hospital University|
|Poitiers, France, 86000|
|Principal Investigator:||Irani Jacques, professor|